GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Peramivir (Rapivab, adults)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Peramivir (Rapivab, adults) - selected U.S. labeling

Product / population
Adult uncomplicated influenza with no more than 2 days of symptoms; intravenous peramivir. Institutional repeated dosing is a separately labeled alternative, not the single-dose label course.
Renal method
Cockcroft-Gault CrCl mL/min; explicitly specified in label Table 1.
Source revision
Label revision date not separately recorded; retrieval date is not the revision date.
Retrieved
2026-09-05
Local review status
Selected dosing/renal sections read; concise local summary, not full prescribing information.
Official

Peramivir (Rapivab, adults) - selected U.S. labeling

Open original reference

U.S. product labeling / DailyMed · Adult uncomplicated influenza with no more than 2 days of symptoms; intravenous peramivir. Institutional repeated dosing is a separately labeled alternative, not the single-dose label course.

Renal method: Cockcroft-Gault CrCl mL/min; explicitly specified in label Table 1.
Source date: Label revision date not separately recorded; retrieval date is not the revision date.
Retrieved: 2026-09-05

Selected dosing/renal sections read; concise local summary, not full prescribing information.

Labeled basic dosing

Creatinine clearance (mL/min)Single IV treatment dose
50 or higher600 mg
30-49200 mg
10-29100 mg

Administer over 15-30 minutes.

RDM31-peramivir-label-dose · Source locator: 2.1; 2.2 Table 1

Renal information and dialysis

Use Cockcroft-Gault CrCl for the adult table. In chronic hemodialysis, give the renal-adjusted dose after dialysis. The label table does not supply a separate below-10 non-dialysis dose.

RDM31-peramivir-label-renal · Source locator: 2.2

Selected warnings and limits

This single-dose label indication should not be conflated with institutional daily treatment for severe illness. Review serious skin/hypersensitivity and neuropsychiatric warnings.

RDM31-peramivir-label-limits · Source locator: 1; 5.1, 5.2

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fe04f6cd-e71c-4bd4-abac-97720bba2a0d
Retrieved
2026-09-05
DailyMed Set ID
fe04f6cd-e71c-4bd4-abac-97720bba2a0d
Renal-function method
Cockcroft-Gault CrCl mL/min; explicitly specified in label Table 1.
Source date/version
Label revision date not separately recorded; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or label PDF.
Local summary SHA-256
6795ab5f40c9da759ee954aab7676e7aeb3b376fb01440e95289e16be0077d1c

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=peramivir&s1=RDM31-label-peramivir&h1=f42704a0732fd64ba59e7759652fca6197025acafe517e3446b7d87464bd89ea