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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Angiomax RTU - labeled renal guidance
Product / population
Bivalirudin (Angiomax RTU), ready-to-use IV infusion for adult PCI
All record notes are retained here, including notes about sources not selected in this review.
Angiomax RTU - product and source limitations
Check activated clotting time 5 minutes after the bolus and monitor anticoagulant status. Keep the indication and infusion concentration with the order.
What to reconcile: Verify the current prescribing information for this presentation.
Check activated clotting time 5 minutes after the bolus and monitor anticoagulant status. Keep the indication and infusion concentration with the order.
Adult renal dosing in this source
PCI population
IV bolus
Infusion during PCI
CrCl <30 mL/min, without HD
0.75 mg/kg
1 mg/kg/hour
Hemodialysis
0.75 mg/kg
0.25 mg/kg/hour
Read the retained text before reformatting
For PCI, the 0.75 mg/kg IV bolus is unchanged in renal impairment. Below CrCl 30 mL/min, lower the procedural infusion to 1 mg/kg/hour. In hemodialysis, use 0.25 mg/kg/hour. Check activated clotting time 5 minutes after the bolus and monitor anticoagulant status. Keep the indication and infusion concentration with the order.
RDM73-angiomax-rtu-official-1 · Source locator: Renal guidance: 2.1, 2.2 and 8.6
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
