GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Rabeprazole sodium (Aciphex), oral delayed-release tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Aciphex - labeled renal guidance

Product / population
Rabeprazole sodium (Aciphex), oral delayed-release tablet
Renal method
CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source revision
DailyMed SPL version 3, posted Jan 30, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Aciphex - product and source limitations

Single-dose data do not establish a supplemental dose or HD timing.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Aciphex - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Rabeprazole sodium (Aciphex), oral delayed-release tablet

Renal method: CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source date: DailyMed SPL version 3, posted Jan 30, 2026
Retrieved: 2026-11-07

Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 12.3 Pharmacokinetics

A single oral 20 mg dose of rabeprazole produced similar pharmacokinetic findings in stable ESRD on maintenance HD and in controls. Single-dose data do not establish a supplemental dose or HD timing.

RDM74-aciphex-official-1 · Source locator: Renal guidance: 12.3 Pharmacokinetics

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1eb38279-0237-4967-be7a-c53a826c1138
Retrieved
2026-11-07
Renal-function method
CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source date/version
DailyMed SPL version 3, posted Jan 30, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
89902390173cc5eccce40e09285c6e39fa5e224aea036494872aaa3afc2d4101

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-aciphex&s1=RDM74-aciphex-official&h1=e1d2434e0578f7b89270d3e8d32b216cbb0ec04d1d8a15fc93cb0995965177d7

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