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Adempas - labeled renal guidance
Product / population
Riociguat (Adempas), oral tablets for pulmonary hypertension
Renal method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 32, effective 2026-08-13; posted Aug 19, 2026
Renal guidance: Highlights, Use in Specific Populations; section 8.6
Use is not recommended for patients on dialysis or with CrCl below 15 mL/min. Safety and efficacy are unestablished in these populations. The label gives no renal starting dose or dialysis supplement.
RDM73-adempas-official-1 · Source locator: Renal guidance: Highlights, Use in Specific Populations; section 8.6
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
