GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Vandetanib (Caprelsa), adult oral tablets

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Caprelsa - labeled renal guidance

Product / population
Vandetanib (Caprelsa), adult oral tablets
Renal method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 15, effective 2026-10-30; posted Nov 04, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Caprelsa - product and source limitations

Monitor QT closely. Dialysis-dependent patients were not studied.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Caprelsa - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Vandetanib (Caprelsa), adult oral tablets

Renal method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date: DailyMed SPL version 15, effective 2026-10-30; posted Nov 04, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.1, 5.12 and 8.6

For CrCl 30 to below 50 mL/min, start at 200 mg once daily. Below 30, use is not recommended. Monitor QT closely. Dialysis-dependent patients were not studied.

RDM73-caprelsa-official-1 · Source locator: Renal guidance: 2.1, 5.12 and 8.6

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e5721cb8-4185-47b9-bbb3-1c587e558a03
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date/version
DailyMed SPL version 15, effective 2026-10-30; posted Nov 04, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
8732943c7fee30c552ccaea49017fd40566627bca50f40a5c4e2b02b12007540

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=vandetanib-caprelsa&s1=RDM73-caprelsa-official&h1=de4f4c0945ac47cb8f6f8ccd47ca0001dde8fb79b4b0fb7fbf3feeb3bbcb19df

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