GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Bupropion hydrobromide (Aplenzin), oral extended-release tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Aplenzin - labeled renal guidance

Product / population
Bupropion hydrobromide (Aplenzin), oral extended-release tablet
Renal method
GFR/eGFR in mL/min as reported by the source
Source revision
DailyMed SPL version 27, posted Mar 05, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Aplenzin - product and source limitations

Verify the ER salt and strength. Hydrobromide and hydrochloride tablet strengths are different.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Aplenzin - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Bupropion hydrobromide (Aplenzin), oral extended-release tablet

Renal method: GFR/eGFR in mL/min as reported by the source
Source date: DailyMed SPL version 27, posted Mar 05, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.7 Dosage Adjustment in Patients with Renal Impairment / 8.6 Renal Impairment

At GFR below 90 mL/min, consider a lower bupropion hydrobromide dose, a less frequent schedule, or both. Verify the ER salt and strength. Hydrobromide and hydrochloride tablet strengths are different.

RDM74-aplenzin-official-1 · Source locator: Renal guidance: 2.7 Dosage Adjustment in Patients with Renal Impairment / 8.6 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6494d2d9-0ce4-4126-b1c7-49684395942b
Retrieved
2026-11-07
Renal-function method
GFR/eGFR in mL/min as reported by the source
Source date/version
DailyMed SPL version 27, posted Mar 05, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
e18537d12f086ba53190a115f12a2cc97f5c45a03107fd4fabbba2bb9742cc97

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-aplenzin&s1=RDM74-aplenzin-official&h1=d9077d6587a97ed37b29b448e959ddb8cbdad5b64030edb34313efc9d425a6df

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