GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Gabapentin immediate-release (Neurontin)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Immediate-release gabapentin only. Do not apply this table to Horizant or Gralise. Source summary and reproduced table use different boundary notation.

Check source scope before reading a dose

NEURONTIN (gabapentin) immediate-release oral products

Product / population
Adults and patients >=12 years for the renal table; not HORIZANT or GRALISE.
Renal method
Not specified
Source revision
Retrieved
2026-09-05
Local review status
Source-read local summary; source-specific recommendations are not automatically interchangeable.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Gabapentin formulations have different renal rules

Immediate-release gabapentin, GRALISE and HORIZANT are not interchangeable renal protocols. HORIZANT also has indication-specific schedules.

What to reconcile: Select the actual formulation and indication before using a dose or dialysis instruction.

Source difference identified; final patient-specific adjudication required.

Open this note and its source references

Exact-30 boundary not resolved by RX table wording

The RX table prints greater-than-30 to 59 and greater-than-15 to 29 bands; dialysis supplements are paired to maintenance regimens.

What to reconcile: Confirm the exact boundary and matched supplement in the complete current product table; no automatic dose calculation is provided.

Source difference identified; final patient-specific adjudication required.

Open this note and its source references

NEURONTIN: printed renal bands leave a boundary unclear

The RX table prints >30 to 59 and >15 to 29; exactly 30 is not clearly assigned. The hemodialysis supplement also belongs with a selected maintenance regimen.

What to reconcile: Verify the current table rather than silently rounding into a band. Do not select a supplement without its corresponding maintenance context.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Official

NEURONTIN (gabapentin) immediate-release oral products

Open original reference

NIH/NLM DailyMed - U.S. prescribing information · Adults and patients >=12 years for the renal table; not HORIZANT or GRALISE.

Renal method: Not specified in this summary.
Source date:
Retrieved: 2026-09-05

Source-read local summary; source-specific recommendations are not automatically interchangeable.

Selected baseline doses

Adult postherpetic neuralgia: 300 mg once on day 1, twice on day 2, three times on day 3; subsequently titrate toward 600 mg three times daily as needed. Epilepsy in patients >=12 years: start 300 mg three times daily; usual maintenance 300-600 mg three times daily.

gabapentin:dm-ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388-1 · Source locator: 2.1-2.2

Label renal table

Cockcroft-Gault CrCl in mL/min; total daily doses: >=60, 900-3600 mg in three doses; >30-59, 400-1400 mg in two doses; >15-29, 200-700 mg once daily; at 15, 100-300 mg once daily. Below 15, reduce proportionately to CrCl.

gabapentin:dm-ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388-2 · Source locator: 2.3, Table 1

Hemodialysis

Use the renal maintenance schedule plus a supplement after each 4-hour HD session: for the five corresponding at-15 maintenance columns (100/125/150/200/300 mg), supplements are 125/150/200/250/350 mg. Do not treat these as interchangeable fixed supplements.

gabapentin:dm-ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388-3 · Source locator: 2.3, Table 1 and footnotes

Source-specific limits

The selected label literally prints >30-59 and >15-29. It does not separately resolve exactly 30; confirm a threshold-boundary regimen with the prescriber rather than silently rounding.

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388
Retrieved
2026-09-05
Exact label title
NEURONTIN (gabapentin) immediate-release oral products
DailyMed Set ID
ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388
Labeler
Parke-Davis Div of Pfizer Inc
DailyMed page updated
2022-07-12
FDA application
New Drug Application
U.S. product identity basis
Exact named product and route appear in the selected U.S. prescription label; current retail availability was not independently assessed.
Hash meaning
Locally authored source summary, not original SPL/XML/PDF bytes
Local summary SHA-256
b1ec3edfc2ebb7e160202e627c37679ca6108146aee4823c8cd9a12d0e824ee2

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=gabapentin&s1=dm-ee9ad9ed-6d9f-4ee1-9d7f-cfad438df388&h1=d7573cd749f536382fc2cd0250d3eb6760720c96a2b4a0a92e858d51b6e1c782