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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
An RX mirror and its underlying label are not independent clinical confirmations.
Check source scope before reading a dose
VYLOY: RX renal pharmacokinetic passage
Product / population
Adult IV VYLOY in the labeled biomarker-selected gastric/GEJ cancer setting. Partner chemotherapy has separate renal requirements.
Renal method
CLcr >=30 to <90 mL/min
Source revision
Not established in reviewed passage
Retrieved
2026-11-07
Local review status
Selected named sections summarized; not a complete monograph or independent clinician approval.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
PK-only evidence must not become a universal no-adjustment rule
The reviewed renal passage is a population-PK statement with a lower studied boundary, not a complete renal dosing algorithm.
What to reconcile: Retain the CLcr metric and limits, and review companion chemotherapy independently.
GlobalRPh RX List / label mirror · Adult IV VYLOY in the labeled biomarker-selected gastric/GEJ cancer setting. Partner chemotherapy has separate renal requirements.
Renal method: CLcr >=30 to <90 mL/min Source date: Not established in reviewed passage Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.
Before using this finding
Confirm product, indication, renal measure and dialysis modality before applying.
Dialysis evidence: No dialysis regimen established in selected content
Selected named sections summarized; not a complete monograph or independent clinician approval.
Selected renal sections
The selected RX passage reports no clinically meaningful clearance effect over CLcr 30 to below 90 mL/min, with severe impairment unknown. Do not promote this PK statement into a general no-adjustment or dialysis rule.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
