GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Ceftazidime / avibactam (Avycaz)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Compare complete versions: U.S. labeling uses 2-hour infusions, while UCSF uses 3-hour extended infusions. Nebraska separately lists an HD/PD interval different from the label. Do not select a dose from one version and an interval from another.

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Avycaz - labeled renal guidance

Product / population
Ceftazidime/avibactam (Avycaz), adult IV combination
Renal method
Cockcroft-Gault creatinine clearance, mL/min
Source revision
DailyMed SPL version 25, effective 2025-04-30; posted Aug 11, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Avycaz - product and source limitations

The FDA label uses a 2-hour infusion. UCSF reports 3 hours and a separate institutional dialysis schedule. Select a complete source before using a dose.

What to reconcile: The FDA label uses a 2-hour infusion. UCSF reports 3 hours and a separate institutional dialysis schedule. Select a complete source before using a dose.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Avycaz - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Ceftazidime/avibactam (Avycaz), adult IV combination

Renal method: Cockcroft-Gault creatinine clearance, mL/min
Source date: DailyMed SPL version 25, effective 2025-04-30; posted Aug 11, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Dialysis evidence: A regimen is reported in selected content

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.3, adult Table 3

Limits that apply to these rows

Give after hemodialysis on HD days. Reassess CrCl at least daily when it is changing. Pediatric eGFR bands have a separate table.

Adult renal dosing in this source
CrCl (mL/min)Total IV combination dose over 2 hoursInterval
31-501.25 gEvery 8 hours
16-300.94 gEvery 12 hours
6-150.94 gEvery 24 hours
<=50.94 gEvery 48 hours
Read the retained text before reformatting

Adult renal doses are total combination grams infused over 2 hours. CrCl 31-50: 1.25 g every 8 hours. At 16-30: 0.94 g every 12 hours. At 6-15: 0.94 g every 24 hours. At <=5: 0.94 g every 48 hours. Give after hemodialysis on HD days. Reassess CrCl at least daily when it is changing. Pediatric eGFR bands have a separate table.

RDM73-avycaz-official-1 · Source locator: Renal guidance: 2.3, adult Table 3

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d9c2803f-dc9c-4b19-b4a3-8303bc8c15fd
Retrieved
2026-11-07
Renal-function method
Cockcroft-Gault creatinine clearance, mL/min
Source date/version
DailyMed SPL version 25, effective 2025-04-30; posted Aug 11, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
e2eb399cc6ea04a368aee14c98016ea740f00965d9db1a60ad5c5b7ca2c653a6

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=ceftazidime-avibactam&s1=RDM73-avycaz-official&h1=c8c35703374f132ab002e9de57cad670d568a759144b919bb14edb768316aa5f

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