Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.
Share or print this source review
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Copy is optional; the link can be selected and copied manually. No patient data or dose decision is collected.
Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Historical indication, duration and organism material is retained. This import does not establish that these are preferred current treatment choices.
Check source scope before reading a dose
Sunnybrook - levofloxacin 750-mg renal strategy
Product / population
Adult systemic levofloxacin; Canadian institutional guidance.
Renal method
CrCl in mL/min; source-specific replacement-therapy schedules.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
Select the usual regimen before the renal row
The 750, 500 and 250 mg renal paths differ. The 250 mg row has a specific uncomplicated-UTI exception and lacks dialysis adjustment information.
What to reconcile: Retain indication, usual dose, loading dose and maintenance interval together.
Sunnybrook Health Sciences Centre, Canada · Adult systemic levofloxacin; Canadian institutional guidance.
Renal method: CrCl in mL/min; source-specific replacement-therapy schedules. Source date: Revision date not stated in the reviewed page. Retrieved: 2026-09-05
Source recheck unresolved. Prior follow-up retrieval/version warning retained; not resolved by v6.0. Read source-review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
Usual schedule: 750 mg daily. CrCl 30-49 mL/min: 750 mg loading, then 500 mg daily; 10-29: 750 mg every 48 hours. Below 10, PD or HD: 750 mg loading, then 500 mg every 48 hours, regardless of HD timing. CRRT retains usual dosing. This institutional approach differs from the UCSF 750-mg renal schedule and must not be blended with it.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.