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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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The separate CRIXIVAN label summary supplies actual historical dosing. It is not presented as missing text recovered from the original GlobalRPh page.
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Renal Drug Handbook, fifth edition
Product / population
Historical 2019 reference; renal bands retain the book's own method labels.
Renal method
Not specified
Source revision
Not established
Retrieved
2026-09-05
Local review status
Historical handbook facts locally summarized; not a current U.S. label or a modern CRRT protocol.
Handbook
Renal Drug Handbook, fifth edition
UK Renal Pharmacy Group / Ashley and Dunleavy / CRC Press · Historical 2019 reference; renal bands retain the book's own method labels.
Renal method: Not specified in this summary. Source date: Not established Retrieved: 2026-09-05
Historical handbook facts locally summarized; not a current U.S. label or a modern CRRT protocol.
Historical renal guidance
The 20-50, 10-20 and <10 mL/min bands retain normal dosing with close monitoring. APD/CAPD, HD and high-flux HDF refer to <10; CAV/VVHD refers to 10-20. The book describes removal as unlikely with APD/CAPD and CAV/VVHD and absent with HD/high-flux HDF.
The handbook discusses crystalluria and nephrolithiasis, including temporary interruption for 1-3 days when flank pain occurs, with or without hematuria.
indinavir:rdh5-521-522-2 · Source locator: Printed page 522: Other information
Source-specific limits
The archived U.S. label states that HD/PD removal is unknown, whereas the book uses more definite dialyzability categories. Preserve this disagreement. This entry is retained from the mandatory GlobalRPh baseline and is not classified as a currently marketed new U.S. drug.
Source identity and provenance
Retrieved
2026-09-05
Handbook page
Printed page 521-522; PDF page 540-541
Hash meaning
Locally authored source summary, not original SPL/XML/PDF bytes
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.