GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Ertapenem (Invanz)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

The source uses indexed renal thresholds but prints an unindexed Cockcroft-Gault formula; preserve the distinction rather than silently treating the units as equivalent.

Check source scope before reading a dose

UCSF - ertapenem

Product / population
Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Daily label regimen versus case-by-case post-HD institutional dosing

The label mirror uses a daily renal regimen with a timing-dependent post-HD supplement. UCSF also offers a selected post-HD-only strategy, with toxicity, age and low-weight qualifications. The source renal units and exactly-30 boundary do not align automatically.

What to reconcile: Use one complete protocol with the dialysis prescription and ID/pharmacy review. Do not add the label supplement to an institutional post-HD dose or silently equate indexed and unindexed clearance.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references

Exactly six hours before HD: overlapping source wording

The label mirror says a supplement is needed within six hours but not needed when the dose is at least six hours before dialysis. The boundary is overlapping as printed.

What to reconcile: Clarify the timing endpoint with the controlling product label and dialysis pharmacist. Do not round an administration time to decide which instruction applies.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Professional

UCSF - ertapenem

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UCSF Infectious Diseases Management Program · Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal method: CrCl in mL/min where specified; no equation inferred.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

IV dosing: CrCl >30 mL/min, 1 g daily; <30, 500 mg daily. The website does not allocate the exact value 30 between these displayed columns; do not invent an inclusive boundary.

IHD: 500 mg initially, then every evening. An alternative is 500 mg to 1 g initially and after subsequent HD sessions, selected case by case with ID pharmacy because toxicity risk matters. Advanced age or weight below 40 kg favors considering 500 mg in that alternative schedule. CVVHD: 1 g daily.

RDM30-005-ertapenem-1 · Source locator: UCSF - ertapenem; renal/dosing sections and stated qualifiers

Source-specific limits

The exact CrCl 30 boundary is incomplete in the website table. Apply an exact current label or an adjudicated institutional rule, not an inferred boundary.

Source identity and provenance
Source
https://idmp.ucsf.edu/content/ertapenem
Retrieved
2026-09-05
Renal-function method
CrCl in mL/min where specified; no equation inferred.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
7a53994666e7e8afb40a502a8e97f833d0a3f9db09724d8bbd7bad776908350a

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=ertapenem&s1=RDM30-005-ertapenem&h1=a1beb591e6a6ac1d90ba6e993b4906dde5bfae25adc299ee83cd64c33cbb16e3