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Aricept - labeled renal guidance
Product / population
Donepezil (Aricept), oral tablets for adults
Renal method
Indexed creatinine clearance, mL/min/1.73 m2
Source revision
DailyMed SPL version 33, effective 2021-12-30; posted Jun 30, 2026
A small PK comparison found similar donepezil clearance in 11 patients with CrCl <18 mL/min/1.73 m2 and 11 matched controls. This finding does not establish a hemodialysis dose or timing rule.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.