GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Donepezil tablets (mild to moderate Alzheimer disease)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

Copy is optional; the link can be selected and copied manually. No patient data or dose decision is collected.

Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Aricept - labeled renal guidance

Product / population
Donepezil (Aricept), oral tablets for adults
Renal method
Indexed creatinine clearance, mL/min/1.73 m2
Source revision
DailyMed SPL version 33, effective 2021-12-30; posted Jun 30, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Aricept - product and source limitations

This finding does not establish a hemodialysis dose or timing rule.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Aricept - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Donepezil (Aricept), oral tablets for adults

Renal method: Indexed creatinine clearance, mL/min/1.73 m2
Source date: DailyMed SPL version 33, effective 2021-12-30; posted Jun 30, 2026
Retrieved: 2026-11-07

Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 12.3, renal disease

A small PK comparison found similar donepezil clearance in 11 patients with CrCl <18 mL/min/1.73 m2 and 11 matched controls. This finding does not establish a hemodialysis dose or timing rule.

RDM73-aricept-official-1 · Source locator: Renal guidance: 12.3, renal disease

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=98e451e1-e4d7-4439-a675-c5457ba20975
Retrieved
2026-11-07
Renal-function method
Indexed creatinine clearance, mL/min/1.73 m2
Source date/version
DailyMed SPL version 33, effective 2021-12-30; posted Jun 30, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
cb77ba928f68effdc9f5a538eb596aabfdd9aa64239f1c18f1055a5571de20a4

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=donepezil-tablets&s1=RDM73-aricept-official&h1=a0bf8787b1c2d6c70339577e088d7d30756f79a5364d0148dd55b599efff40b8

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