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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Primaxin I.V. - labeled renal guidance
Product / population
Imipenem and cilastatin sodium (Primaxin I.V.), IV injection
All record notes are retained here, including notes about sources not selected in this review.
Primaxin I.V. - product and source limitations
Use stable serum creatinine. The label restricts use below CrCl 15 unless hemodialysis is instituted within 48 hours. Confirm seizure risk and HD timing.
What to reconcile: Apply only to the stated formulation, indication and renal population.
Renal guidance: 2.3 Dosage in Adult Patients with Renal Impairment / 8.6 Renal Impairment
Adult CrCl below 90 mL/min requires a lower imipenem/cilastatin IV regimen. Use the label's renal table and the row for the intended regimen and organism susceptibility. Use stable serum creatinine. The label restricts use below CrCl 15 unless hemodialysis is instituted within 48 hours. Confirm seizure risk and HD timing.
RDM74-primaxin-iv-official-1 · Source locator: Renal guidance: 2.3 Dosage in Adult Patients with Renal Impairment / 8.6 Renal Impairment
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
