GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Aliskiren hemifumarate (Tekturna), oral tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Tekturna - labeled renal guidance

Product / population
Aliskiren hemifumarate (Tekturna), oral tablet
Renal method
Renal impairment categories as defined by the cited product label
Source revision
DailyMed SPL version 16, posted Mar 12, 2024
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Tekturna - product and source limitations

This is an interaction restriction. Review combined renin-angiotensin blockade, potassium, and renal function.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Tekturna - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Aliskiren hemifumarate (Tekturna), oral tablet

Renal method: Renal impairment categories as defined by the cited product label
Source date: DailyMed SPL version 16, posted Mar 12, 2024
Retrieved: 2026-11-07

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 5.2 Renal Impairment/Hyperkalemia/Hypotension when Tekturna is Given in Combination with ARBs or ACEIs / 5.5 Impaired Renal Function / 8.6 Renal Impairment

Aliskiren is contraindicated with an ACE inhibitor or ARB in diabetes because the combination increases the risk of kidney injury, hypotension and hyperkalemia. This is an interaction restriction. Review combined renin-angiotensin blockade, potassium, and renal function.

RDM74-tekturna-official-1 · Source locator: Renal guidance: 5.2 Renal Impairment/Hyperkalemia/Hypotension when Tekturna is Given in Combination with ARBs or ACEIs / 5.5 Impaired Renal Function / 8.6 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3dd61fa5-1620-4ebf-bbdb-ede29b92fce2
Retrieved
2026-11-07
Renal-function method
Renal impairment categories as defined by the cited product label
Source date/version
DailyMed SPL version 16, posted Mar 12, 2024
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
26f40a2b1a0a578b09a7a72ed5c25a1a76162734cb19c8de9ffe80906846e577

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-tekturna&s1=RDM74-tekturna-official&h1=9e4ee4828dc8314e46d41c09658854bcdbbd10e7c509e9a2d008b28c706eba29

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