GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Doravirine (Pifeltro), single-ingredient oral tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Pifeltro - HHS HIV guidelines panel / ClinicalInfo

Product / population
Single-ingredient doravirine in adult/adolescent HIV care.
Renal method
Renal adjustment column for doravirine alone.
Source revision
Online guidance checked 2026-11-07; section revision not established.
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Pifeltro - product and source limitations

ESRD was inadequately studied and dialysis patients were not studied. This guidance applies to single-ingredient doravirine.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Professional

Pifeltro - HHS HIV guidelines panel / ClinicalInfo

Open original reference

HHS HIV guidelines panel / ClinicalInfo · Single-ingredient doravirine in adult/adolescent HIV care.

Renal method: Renal adjustment column for doravirine alone.
Source date: Online guidance checked 2026-11-07; section revision not established.
Retrieved: 2026-11-07

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Appendix B, doravirine row

The panel lists the usual adult 100 mg oral daily dose without renal adjustment. This recommendation is specific to doravirine alone; evaluate renal limits of companion agents separately. The product label describes limited ESRD evidence.

RDM73-pifeltro-professional-1 · Source locator: Appendix B, doravirine row

Source identity and provenance
Source family
professional_guideline
Source
https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/drug-characteristics-tables-renal-hepatic-insufficiency-full
Retrieved
2026-11-07
Renal-function method
Renal adjustment column for doravirine alone.
Source date/version
Online guidance checked 2026-11-07; section revision not established.
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
5611e64598a64bd50e9f6838b8309ea8de24eba734bfdce819760e5b9b5b0fe3

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=doravirine-pifeltro&s1=RDM73-pifeltro-professional&h1=9b3b501e33f5eaddf3e09425ad258b68d8cea102242fd7a5dc08ca0973620a40

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