GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Ertapenem (Invanz)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

The source uses indexed renal thresholds but prints an unindexed Cockcroft-Gault formula; preserve the distinction rather than silently treating the units as equivalent.

Check source scope before reading a dose

UCSF adult ertapenem renal and dialysis guidance

Product / population
UCSF adult institutional ertapenem: non-dialysis, intermittent HD and continuous HD. Not universal CRRT guidance.
Renal method
CrCl mL/min; modality-specific institutional schedules.
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-07
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Daily label regimen versus case-by-case post-HD institutional dosing

The label mirror uses a daily renal regimen with a timing-dependent post-HD supplement. UCSF also offers a selected post-HD-only strategy, with toxicity, age and low-weight qualifications. The source renal units and exactly-30 boundary do not align automatically.

What to reconcile: Use one complete protocol with the dialysis prescription and ID/pharmacy review. Do not add the label supplement to an institutional post-HD dose or silently equate indexed and unindexed clearance.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references

Exactly six hours before HD: overlapping source wording

The label mirror says a supplement is needed within six hours but not needed when the dose is at least six hours before dialysis. The boundary is overlapping as printed.

What to reconcile: Clarify the timing endpoint with the controlling product label and dialysis pharmacist. Do not round an administration time to decide which instruction applies.

Source-specific interpretation; independent clinician adjudication pending.

Open this note and its source references
Professional

UCSF adult ertapenem renal and dialysis guidance

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University of California San Francisco · UCSF adult institutional ertapenem: non-dialysis, intermittent HD and continuous HD. Not universal CRRT guidance.

Renal method: CrCl mL/min; modality-specific institutional schedules.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

UCSF lists 1 g IV every 24 hours above CrCl 30 and 500 mg every 24 hours below 30; exactly 30 is not assigned by its printed inequalities. Intermittent HD: 500 mg once now, then each evening; alternatively 500 mg to 1 g once now, then after HD. The post-HD-only strategy is case-by-case because of toxicity risk; consider 500 mg in advanced age or body weight under 40 kg and consult ID pharmacy. Continuous HD: 1 g every 24 hours. Do not generalize that row to all CRRT prescriptions.

RDM43-professional-ertapenem-b0bd191d14-C1 · Source locator: Adult non-dialysis and intermittent/continuous hemodialysis tables; post-HD footnote.

Source identity and provenance
Source family
professional_guidance
Source
https://idmp.ucsf.edu/content/ertapenem
Retrieved
2026-09-07
Renal-function method
CrCl mL/min; modality-specific institutional schedules.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
ed30af8abe5571ed53cac130d078961b728e4f1fe4f4a5ee00b7b0aa26282507

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=ertapenem&s1=RDM43-professional-ertapenem-b0bd191d14&h1=993f7fd23bfde5bbbafbf7a8c2866729cf8451d4a1ff5b4a4184d2e2bfb25894