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Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Alunbrig - labeled renal guidance
Product / population
Brigatinib (Alunbrig), adult oral tablets
Renal method
Cockcroft-Gault creatinine clearance, mL/min
Source revision
DailyMed SPL version 17, effective 2026-01-12; posted Jan 19, 2026
At CrCl 15-29 mL/min, use the label's specified lower step: 180 mg becomes 90 mg daily, and 90 mg becomes 60 mg daily. At 30-89, no renal reduction is recommended. The supplied dose steps take precedence over a calculated percentage. Below 15 and dialysis are outside these bands.
RDM73-alunbrig-official-1 · Source locator: Renal guidance: 2.7 and 8.7
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
