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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Compare complete versions: U.S. labeling uses 2-hour infusions, while UCSF uses 3-hour extended infusions. Nebraska separately lists an HD/PD interval different from the label. Do not select a dose from one version and an interval from another.
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AVYCAZ - adult U.S. label renal table
Product / population
Adults; exact named U.S. product. Selected dose/renal summary, not the full prescribing information.
Renal method
Cockcroft-Gault CrCl, mL/min.
Source revision
Label revised April 2025; DailyMed updated 2025-04-30.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Locally included source-specific summary. Regimen differences are not automatically resolved.
Dosing / renal protocol and limits
Adult labeled cIAI, cUTI/pyelonephritis and HABP/VABP dosing uses total combination grams, all infused IV over 2 hours.
Cockcroft-Gault CrCl (mL/min)
Dose
Interval
>50
2.5 g
Every 8 hours
31-50
1.25 g
Every 8 hours
16-30
0.94 g
Every 12 hours
6-15
0.94 g
Every 24 hours
<=5
0.94 g
Every 48 hours
On HD days, administer after dialysis. For changing renal function, reassess clearance at least daily. Adult cIAI treatment also includes metronidazole. This label's 2-hour infusion differs from the UCSF 3-hour strategy; its <=5 band also resolves a boundary omitted by that institutional page. Pediatric dosing requires a separate age/eGFR table, not this adult table.
RDM30-067-ceftazidime-avibactam-1 · Source locator: AVYCAZ - adult U.S. label renal table; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.