GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Canagliflozin - source Invokana/Invokamet statement

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Product mismatch in the original source: the heading says INVOKANA but the body describes INVOKAMET. The complete original statement is preserved; do not apply its combination-product instructions to single-agent canagliflozin.

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Invokana - labeled renal guidance

Product / population
Canagliflozin (Invokana), adult single-ingredient oral tablets
Renal method
Indexed GFR/eGFR, mL/min/1.73 m2
Source revision
DailyMed SPL version 9, effective 2026-09-21; posted Sep 23, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Invokana - product and source limitations

Use the prescribing information's separate UGT-inducer instructions when applicable. This continuation exception does not transfer to canagliflozin/metformin.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Invokana - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Canagliflozin (Invokana), adult single-ingredient oral tablets

Renal method: Indexed GFR/eGFR, mL/min/1.73 m2
Source date: DailyMed SPL version 9, effective 2026-09-21; posted Sep 23, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2, renal impairment and interacting drugs

For adults with eGFR 30 to <60, the usual renal maximum is 100 mg once daily. Below 30, initiation is not recommended. Adults already taking it who have albuminuria >300 mg/day may continue 100 mg daily for the labeled cardiorenal indication. Use the prescribing information's separate UGT-inducer instructions when applicable. This continuation exception does not transfer to canagliflozin/metformin.

RDM73-invokana-official-1 · Source locator: Renal guidance: 2, renal impairment and interacting drugs

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4e946ba3-02c4-4a10-9d5e-f2d87b534dc3
Retrieved
2026-11-07
Renal-function method
Indexed GFR/eGFR, mL/min/1.73 m2
Source date/version
DailyMed SPL version 9, effective 2026-09-21; posted Sep 23, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
d9b9912131383a1483adc39cc31ff84a20c8a2d76e50d2f31ac5c066d2cfafbd

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=general-canagliflozin&s1=RDM73-invokana-official&h1=82c06ce01cd6385644cc55cea95cdf8a18e19181b729f5b074b70fc323cf4eee

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