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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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GlobalRPh RX List - CUBICIN RF
Product / population
Adult intravenous daptomycin. Product preparation, infection indication and institution-specific higher-dose regimens must remain separately attributed.
Renal method
CrCl in mL/min; selected PK table specifies Cockcroft-Gault using actual body weight
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-10
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
Do not merge label and higher-dose institutional dialysis protocols
The label includes CrCl exactly 30 in its >=30 band. UCSF prints >30 and <30, omitting exactly 30, and uses higher doses and different HD scheduling.
What to reconcile: Keep source-specific dose, interval, indication, weight basis and modality together. The official threshold is explicit; seek institutional clarification rather than silently changing its headings.
GlobalRPh-hosted RX List · Adult intravenous daptomycin. Product preparation, infection indication and institution-specific higher-dose regimens must remain separately attributed.
Renal method: CrCl in mL/min; selected PK table specifies Cockcroft-Gault using actual body weight Source date: Source revision date not established in selected retrieval. Retrieved: 2026-09-10
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding
Keep the infection-specific dose, interval and dialysis schedule from the same source.
Dialysis evidence: A regimen is reported in selected content
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
The CUBICIN RF mirror gives 4 mg/kg every 24 hours for adult complicated skin/skin-structure infection and 6 mg/kg every 24 hours for adult S. aureus bloodstream infection when CrCl is at least 30 mL/min. Below 30, including HD and CAPD, the respective doses are given every 48 hours; administer after HD when possible. Pediatric renal dosing is not established. In renal impairment, renal function and CPK need assessment more frequently than weekly. These indication-specific label regimens are not the UCSF higher-dose protocol.
Selected named sections only; not a complete monograph or independent clinical approval.
A label mirror is not independent corroboration of its underlying label. See the separately attributed official source; concordance is limited to selected sections.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.