One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
The original page contains two different IV renal band sets (25/50 versus 30/50) and an indexed CrCl table. They are preserved separately, not reconciled into one recommendation. Confirm the applicable current product label before clinical use.
The printed bands overlap at exactly 25. Do not choose a boundary by assumption.
UCSF uses actual weight unless above 120% of ideal, then adjusted weight; this differs from ideal-weight labeling in obesity. These are IV regimens. Reassess dialysis prescription and residual function.
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >50 | 5 mg/kg every 8 hours |
| 25-50 | 5 mg/kg every 12 hours |
| 10-25 | 5 mg/kg every 24 hours |
| <10 | 2.5 mg/kg every 24 hours |
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >50 | 10 mg/kg every 8 hours |
| 25-50 | 10 mg/kg every 12 hours |
| 10-25 | 10 mg/kg every 24 hours |
| <10 | 5 mg/kg every 24 hours |
| Dialysis setting / indication | Source-specific schedule |
|---|---|
| Intermittent HD - non-CNS HSV | 2.5 mg/kg initially and each evening |
| Intermittent HD - encephalitis/disseminated VZV | 5 mg/kg initially and each evening |
| Continuous HD - non-CNS HSV | 5 mg/kg every 24 hours |
| Continuous HD - encephalitis/disseminated VZV | 10 mg/kg every 12 hours |
CrCl >50 / 25-50 / 10-25 / <10 mL/min: non-CNS HSV uses 5 mg/kg IV every 8 / 12 / 24 hours, then 2.5 mg/kg daily in the lowest band. Encephalitis or disseminated VZV uses 10 mg/kg every 8 / 12 / 24 hours, then 5 mg/kg daily. The source overlaps at exactly 25.
Intermittent HD: non-CNS HSV 2.5 mg/kg initially and each evening; encephalitis/disseminated VZV 5 mg/kg initially and each evening. Continuous HD: non-CNS HSV 5 mg/kg daily; encephalitis/disseminated VZV 10 mg/kg every 12 hours.
UCSF uses actual weight unless above 120% of ideal, then adjusted weight; its discussion acknowledges disagreement with ideal-weight labeling for obesity. These are institutional IV regimens, not oral dosing. Dialysis prescription and residual function can materially change requirements.
RDM30-033-acyclovir-1 · Source locator: UCSF - acyclovir intravenous: HSV, VZV and dialysis; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=acyclovir&s1=RDM30-033-acyclovir&h1=7ce092b01793e44936b5c5a74807f21d61cd26fe0d0a3d9d9a5bb20260381b2d