GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Avatrombopag maleate (Doptelet), oral tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Doptelet - labeled renal guidance

Product / population
Avatrombopag maleate (Doptelet), oral tablet
Renal method
Cockcroft-Gault CrCl, mL/min
Source revision
DailyMed SPL version 21, posted Aug 15, 2025
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Doptelet - product and source limitations

Select the indicated regimen and monitor platelets. No renal adjustment can be derived from this evidence gap.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Doptelet - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Avatrombopag maleate (Doptelet), oral tablet

Renal method: Cockcroft-Gault CrCl, mL/min
Source date: DailyMed SPL version 21, posted Aug 15, 2025
Retrieved: 2026-11-07

Limited or unstudied renal evidence. Not studied does not mean no adjustment is required.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 12.3 Pharmacokinetics

The effect of Cockcroft-Gault CrCl below 30 mL/min, including hemodialysis, on avatrombopag disposition is unknown. Select the indicated regimen and monitor platelets. No renal adjustment can be derived from this evidence gap.

RDM74-doptelet-official-1 · Source locator: Renal guidance: 12.3 Pharmacokinetics

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e2d5960d-6c18-46cc-86bd-089222b09852
Retrieved
2026-11-07
Renal-function method
Cockcroft-Gault CrCl, mL/min
Source date/version
DailyMed SPL version 21, posted Aug 15, 2025
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
2d6d49fad03378227174072d6c99ccfb08fd9688ee122e22c48044650b5924bd

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-doptelet&s1=RDM74-doptelet-official&h1=7c9df8fd680b7f10cc4dbaaed7a8f211ec21b92187fb9c045679a9b505135c6f

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