GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Romosozumab - EVENITY subcutaneous injection

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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EVENITY - official renal safety check

Product / population
EVENITY - official renal safety check; selected renal passages, not a complete prescribing monograph.
Renal method
eGFR, mL/min/1.73 m2; preserve body-surface-area indexing.
Source revision
Prescribing information revised January 2026.
Retrieved
2026-09-09
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

No renal adjustment does not remove hypocalcemia or cardiovascular safeguards

The two sources agree on no renal adjustment while retaining high-risk calcium monitoring. Nonrenal eligibility remains separate.

What to reconcile: Check calcium status and complete product eligibility. Do not import PROLIA monitoring intervals or invent a smaller renal dose.

Source-specific interpretation; independent clinician adjudication pending.

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Official

EVENITY - official renal safety check

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DailyMed / Amgen Inc. · EVENITY - official renal safety check; selected renal passages, not a complete prescribing monograph.

Renal method: eGFR, mL/min/1.73 m2; preserve body-surface-area indexing.
Source date: Prescribing information revised January 2026.
Retrieved: 2026-09-09

Monitoring or renal-toxicity guidance. This finding concerns risk or surveillance; it may not establish a dose adjustment.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The label retains no renal dose adjustment alongside greater hypocalcemia risk at eGFR 15-29 mL/min/1.73 m2 or during dialysis. Correct low calcium beforehand, monitor serum calcium in these high-risk patients, and provide calcium/vitamin D. No renal adjustment does not establish overall treatment eligibility: do not initiate EVENITY in a patient with myocardial infarction or stroke within the preceding year. No numerical renal dose reduction or fixed calcium-monitoring interval is inferred from these sections.

RDM52-official-romosozumab-evenity-7c3f920f54-C1 · Source locator: Sections 8.7, 5.3 and 5.1; prescribing-information revision and label header.

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=471baba2-7154-4488-9891-0db2f46791e7
Retrieved
2026-09-09
Exact label title
EVENITY - romosozumab-aqqg injection, solution
DailyMed Set ID
471baba2-7154-4488-9891-0db2f46791e7
Labeler
Amgen Inc.
DailyMed page updated
2026-07-16
Label revision
Prescribing information revised January 2026.
FDA application
BLA761062
Renal-function method
eGFR, mL/min/1.73 m2; preserve body-surface-area indexing.
Source date/version
Prescribing information revised January 2026.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
da91a38e0151ab3050bdef447dcd92c950a72e217a36a2666da48bfc0891e183

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=romosozumab-evenity&s1=RDM52-official-romosozumab-evenity-7c3f920f54&h1=7b7e0869fb634fbcd988604148d26d3252c7de61bcd47902baaeca6c098d5ff2