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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Check source scope before reading a dose
UCSF cefiderocol - fresh institutional follow-up
Product / population
Adult cefiderocol IV; distinguish non-dialysis CrCl from intermittent HD and CRRT effluent. Institutional protocols remain separately attributed.
Renal method
CrCl mL/min (equation not specified on this page); continuous-dialysis effluent L/hour
Source revision
Source revision date not established in selected retrieval.
Retrieved
2026-09-10
Local review status
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
CRRT effluent guidance is not an intermittent-HD dose table
The selected official and mirror tables agree. Their CRRT guidance is explicitly initial and depends on effluent rather than a CrCl band.
What to reconcile: Confirm modality and L/hour effluent, then reassess residual function and clinical status; do not interpolate a new algorithm.
The recovered institutional page has different printed boundaries
The official label uses CrCl >=120; UCSF prints >120 beside 60-119. The upper effluent band is >=4.1 L/hour in the label versus >4 in UCSF.
What to reconcile: For exactly CrCl 120 the official label is explicit. Preserve the institutional discrepancy and seek clarification for effluent values between printed bands; do not interpolate. This is a wording/boundary comparison, not evidence of different clinical outcomes.
UCSF Infectious Diseases Management Program · Adult cefiderocol IV; distinguish non-dialysis CrCl from intermittent HD and CRRT effluent. Institutional protocols remain separately attributed.
Renal method: CrCl mL/min (equation not specified on this page); continuous-dialysis effluent L/hour Source date: Source revision date not established in selected retrieval. Retrieved: 2026-09-10
Professional guidance with defined scope. Publication date, institutional setting and source limitations remain controlling. This is not automatic preference over another source.
Before using this finding
Retrieval failure resolved; the numeric-boundary discrepancy remains open.
Institutional >120 is not identical to the label >=120.
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
The institutional table lists 2 g every 6 hours for CrCl >120 mL/min and 2 g every 8 hours for 60-119. Its other non-dialysis doses and intermittent-HD 750 mg every 12 hours align with the selected official table; infusions run over 3 hours.
Its continuous-dialysis bands use effluent <=2, 2.1-3, 3.1-4 and >4 L/hour, paired respectively with 1.5 g every 12 hours, 2 g every 12 hours, 1.5 g every 8 hours and 2 g every 8 hours. Use is restricted to Infectious Diseases or Antimicrobial Stewardship.
Exactly CrCl 120 is omitted by the printed >120 and 60-119 headings. The upper effluent boundary is >4 rather than the label's >=4.1. Preserve both differences; do not imply a new interpolation rule.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.