One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Historical indication, duration and organism material is retained. This import does not establish that these are preferred current treatment choices.
The 750, 500 and 250 mg renal paths differ. The 250 mg row has a specific uncomplicated-UTI exception and lacks dialysis adjustment information.
What to reconcile: Retain indication, usual dose, loading dose and maintenance interval together.
Open this note and its source referencesExactly 50 is unassigned in this source. Separate oral doses from multivalent cations by at least 2 hours.
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >50 | 500 mg every 24 hours |
| 20-49 | 500 mg once, then 250 mg every 24 hours |
| <20 | 500 mg once, then 250 mg every 48 hours |
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >50 | 750 mg every 24 hours |
| 20-49 | 750 mg every 48 hours |
| <20 | 750 mg once, then 500 mg every 48 hours |
| Dialysis setting / indication | Source-specific schedule |
|---|---|
| IHD standard | 500 mg once, then 250 mg every 48 hours |
| IHD pneumonia/Gram-negative bacteremia/Pseudomonas | 750 mg once, then 500 mg every 48 hours |
| CVVHD standard | 750 mg once, then 250 mg every 24 hours |
| CVVHD pneumonia/bacteremia/Pseudomonas | 750 mg once, then 500 mg IV every 24 hours |
For CrCl >50 / 20-49 / <20 mL/min, UTI treatment uses 500 mg IV/orally daily / 500 mg once then 250 mg daily / 500 mg once then 250 mg every 48 hours. Other infections use 750 mg daily / 750 mg every 48 hours / 750 mg once then 500 mg every 48 hours.
IHD standard: 500 mg once then 250 mg every 48 hours. IHD pneumonia, Gram-negative bacteremia or Pseudomonas: 750 mg once then 500 mg every 48 hours.
CVVHD standard: 750 mg once then 250 mg daily; pneumonia/bacteremia/Pseudomonas: 750 mg once then 500 mg IV daily. Oral doses require separation from multivalent cations by at least 2 hours.
The exact CrCl 50 boundary is not allocated by the displayed >50 / 20-49 columns.
RDM30-015-levofloxacin-1 · Source locator: UCSF - levofloxacin; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=levofloxacin&s1=RDM30-015-levofloxacin&h1=6748148cb53d8e11d610864959271beddaae6803c22b19a6e796db379b302504