GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Topiramate (Trokendi XR), oral extended-release capsule

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Trokendi XR - labeled renal guidance

Product / population
Topiramate (Trokendi XR), oral extended-release capsule
Renal method
CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source revision
DailyMed SPL version 31, posted Oct 06, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Trokendi XR - product and source limitations

Hemodialysis can remove topiramate. Consult the dialysis section for session-specific considerations.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Trokendi XR - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Topiramate (Trokendi XR), oral extended-release capsule

Renal method: CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source date: DailyMed SPL version 31, posted Oct 06, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.5 Dose Modifications in Patients With Renal Impairment / 8.6 Renal Impairment

At CrCl below 70 mL/min/1.73 m2 use half the usual adult extended-release topiramate dose for the indication. Hemodialysis can remove topiramate. Consult the dialysis section for session-specific considerations.

RDM74-trokendi-xr-official-1 · Source locator: Renal guidance: 2.5 Dose Modifications in Patients With Renal Impairment / 8.6 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dc7957e-a3e5-46bb-aa66-f3250f872f5e
Retrieved
2026-11-07
Renal-function method
CrCl normalized to 1.73 m2, mL/min/1.73 m2
Source date/version
DailyMed SPL version 31, posted Oct 06, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
0ad6ef66283c0b89bb223f49b1426933057bb90b7b16492da4d3bf8aa71fb3a3

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-trokendi-xr&s1=RDM74-trokendi-xr-official&h1=61187055cb16e060f202ec16cba02724faa28d2416ac8ef19d71489a2945e71a

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