GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Ceftazidime / avibactam (Avycaz)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Compare complete versions: U.S. labeling uses 2-hour infusions, while UCSF uses 3-hour extended infusions. Nebraska separately lists an HD/PD interval different from the label. Do not select a dose from one version and an interval from another.

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UCSF - AVYCAZ extended-infusion protocol

Product / population
Adults; IV ceftazidime/avibactam combined dose; ID/antimicrobial-stewardship restricted.
Renal method
CrCl in mL/min where specified; no equation inferred.
Source revision
Revision date not stated in the reviewed page.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Professional

UCSF - AVYCAZ extended-infusion protocol

Open original reference

UCSF Infectious Diseases Management Program · Adults; IV ceftazidime/avibactam combined dose; ID/antimicrobial-stewardship restricted.

Renal method: CrCl in mL/min where specified; no equation inferred.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Limits that apply to these rows

The columns omit exactly 5. All these institutional infusions last 3 hours; do not silently substitute the product-label infusion duration.

Combination amount - IV over 3 hours
CrCl, mL/minSource-specific dose / instruction
>502.5 g every 8 hours
31-501.25 g every 8 hours
16-300.94 g every 12 hours
6-150.94 g every 24 hours
<50.94 g every 48 hours
Dialysis guidance - separate source-specific schedules
Ceftazidime/avibactam - dialysis
Dialysis setting / indicationSource-specific schedule
IHD0.94 g initially, then each evening
IHD alternative - minimal residual function and less severe infection0.94 g every 48 hours in the evening
CVVHD2.5 g every 8 hours
Read the retained text before reformatting

Doses refer to the combined product and are infused IV over 3 hours. CrCl columns as published (>50 / 31-50 / 16-30 / 6-15 / <5 mL/min) correspond to 2.5 g every 8 hours / 1.25 g every 8 hours / 0.94 g every 12 hours / 0.94 g daily / 0.94 g every 48 hours.

The published columns omit exactly 5 mL/min; that boundary is not repaired by assumption.

IHD: 0.94 g initially, then each evening. For minimal residual kidney function and less severe infection, an alternative is 0.94 g every 48 hours in the evening. CVVHD: 2.5 g every 8 hours. All these institutional infusions last 3 hours; retain separately from product-label infusion instructions.

RDM30-006-ceftazidime-avibactam-1 · Source locator: UCSF - AVYCAZ extended-infusion protocol; renal/dosing sections and stated qualifiers

Source-specific limits

The website writes <5 rather than <=5. Exact-boundary ambiguity is retained.

Source identity and provenance
Source
https://idmp.ucsf.edu/content/ceftazidime-avibactam-avycaz
Retrieved
2026-09-05
Renal-function method
CrCl in mL/min where specified; no equation inferred.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
7f22beac10b55f90715c9060361449aeb7e77eafafd64a883f76716478d7edb7

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=ceftazidime-avibactam&s1=RDM30-006-ceftazidime-avibactam&h1=4c596d50e43379bdad70fe165f49f16f593ba3f62edab390595a92d2be6a3399