GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Eravacycline (Xerava)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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XERAVA - adult cIAI dosing and renal statement

Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method
No renal-function dose bands specified for this summary.
Source revision
DailyMed updated 2025-03-31; prescribing information revised 2025-03
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Official

XERAVA - adult cIAI dosing and renal statement

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NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Source date: DailyMed updated 2025-03-31; prescribing information revised 2025-03
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Adults with complicated intra-abdominal infection: 1 mg/kg IV every 12 hours, infused over approximately 60 minutes, for 4-14 days according to response. This is not a cUTI indication.

Renal impairment does not require dose adjustment. Hemodialysis is not expected to remove substantial drug.

Severe hepatic impairment is different: Child-Pugh C uses 1 mg/kg every 12 hours on day 1, then every 24 hours. Strong CYP3A inducers require 1.5 mg/kg every 12 hours. Confirm interacting drugs and hepatic function rather than applying the renal statement to these situations.

RDM30-091-eravacycline-1 · Source locator: XERAVA - adult cIAI dosing and renal statement; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4b188d4-f467-470c-ad7b-25ffbdd8862a
Retrieved
2026-09-05
DailyMed Set ID
a4b188d4-f467-470c-ad7b-25ffbdd8862a
Renal-function method
No renal-function dose bands specified for this summary.
Source date/version
DailyMed updated 2025-03-31; prescribing information revised 2025-03
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
1306211a715a1b82ff2a60314dea07fcae25d96eb4ffccc258f25390b986de3f

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=eravacycline&s1=RDM30-091-eravacycline&h1=45ff062a2a7f8c3d3a14a0875055f4e64d8924e1f8ad93b5e4f8683be60c8f38