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Pemfexy - labeled renal guidance
Product / population
Pemetrexed (Pemfexy), IV solution for dilution, adults
Renal method
Cockcroft-Gault creatinine clearance, mL/min
Source revision
DailyMed SPL version 2, effective 2026-06-18; posted Jun 23, 2026
Withhold at CrCl below 45 mL/min. At 45-79, withhold ibuprofen for the two days preceding the dose, the treatment day and the following two days. Check CrCl before every cycle. If ibuprofen is necessary, monitor hematologic, renal and GI toxicity more frequently.
RDM73-pemfexy-official-1 · Source locator: Renal guidance: 2.3, 2.5 and 5.2
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
