GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Linagliptin - single agent (Tradjenta)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

Share or print this source review

1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

Copy is optional; the link can be selected and copied manually. No patient data or dose decision is collected.

Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

TRADJENTA single agent - adult renal dosing

Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal method
No renal-function dose bands specified for this summary.
Source revision
DailyMed updated 2025-03-21; prescribing text revised June 2023.
Retrieved
2026-09-05
Local review status
Locally included source-specific summary. Regimen differences are not automatically resolved.
Official

TRADJENTA single agent - adult renal dosing

Open original reference

NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Source date: DailyMed updated 2025-03-21; prescribing text revised June 2023.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Adult type 2 diabetes: 5 mg orally once daily, with or without food. No renal dose adjustment is recommended. This statement is for single-agent linagliptin, not a linagliptin/metformin combination. Review pancreatitis, heart-failure and hypersensitivity precautions, and consider reducing insulin or secretagogue doses to limit hypoglycemia. Strong P-glycoprotein/CYP3A4 inducers can reduce efficacy.

RDM30-084-linagliptin-1 · Source locator: TRADJENTA single agent - adult renal dosing; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c797ea5c-cab7-494b-9044-27eba0cfe40f
Retrieved
2026-09-05
DailyMed Set ID
c797ea5c-cab7-494b-9044-27eba0cfe40f
Renal-function method
No renal-function dose bands specified for this summary.
Source date/version
DailyMed updated 2025-03-21; prescribing text revised June 2023.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
1681e9cebfe985eca856307978cbd41cf56d6bb0f11c54c8fb6f12381d1ad22e

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=linagliptin&s1=RDM30-084-linagliptin&h1=3ba06ddfba6807b7747db5d5b123b25928f2891ad9cd5f774ddbbf5486b9f151