GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Irbesartan (Avapro), adult oral tablets for hypertension

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Avapro - labeled renal guidance

Product / population
Irbesartan (Avapro), adult oral tablets for hypertension
Renal method
Intravascular volume or salt depletion; no numerical renal cutoff for this starting dose
Source revision
DailyMed SPL version 22, effective 2026-08-24; posted Aug 31, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Avapro - product and source limitations

Assess volume status and blood pressure first. This lower starting dose addresses depletion; it is not a dose to repeat after every dialysis session.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Avapro - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Irbesartan (Avapro), adult oral tablets for hypertension

Renal method: Intravascular volume or salt depletion; no numerical renal cutoff for this starting dose
Source date: DailyMed SPL version 22, effective 2026-08-24; posted Aug 31, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: Dosage in volume- and salt-depleted patients; 5.2 and 5.3

When intravascular volume or salt is depleted, including in some patients on hemodialysis or receiving intensive diuresis, start at 75 mg once daily. Assess volume status and blood pressure first. This lower starting dose addresses depletion; it is not a dose to repeat after every dialysis session.

RDM73-avapro-official-1 · Source locator: Renal guidance: Dosage in volume- and salt-depleted patients; 5.2 and 5.3

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7885b2a8-be4e-48ab-8113-4e6ab791eb98
Retrieved
2026-11-07
Renal-function method
Intravascular volume or salt depletion; no numerical renal cutoff for this starting dose
Source date/version
DailyMed SPL version 22, effective 2026-08-24; posted Aug 31, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
0fbc4ba96e6c19df322dda25a04b9d08729a983beb439541be64051c8277d8dc

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=irbesartan-avapro&s1=RDM73-avapro-official&h1=388433ece40d42bad085fcceb34ac443a050befb301ddd4a8d84f1c37455f1ae

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