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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Mavik - labeled renal guidance
Product / population
Trandolapril (Mavik), adult oral tablets
Renal method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 2, effective 2012-02-14; posted Feb 15, 2012
Renal guidance: Dosage adjustment in renal impairment
For CrCl below 30 mL/min, start at 0.5 mg daily. Adjust subsequently according to response. Reduced clearance also occurs in dialysis. The selected section does not give a replacement dose after dialysis.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
