GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Aliskiren hemifumarate and hydrochlorothiazide (Tekturna HCT), oral tablet

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Tekturna HCT - labeled renal guidance

Product / population
Aliskiren hemifumarate and hydrochlorothiazide (Tekturna HCT), oral tablet
Renal method
Creatinine clearance (CrCl), mL/min
Source revision
DailyMed SPL version 11, posted Nov 17, 2022
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Tekturna HCT - product and source limitations

Consider the thiazide component and the specific restrictions on concurrent ACE inhibitors or ARBs.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Tekturna HCT - labeled renal guidance

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DailyMed / product prescribing information · Aliskiren hemifumarate and hydrochlorothiazide (Tekturna HCT), oral tablet

Renal method: Creatinine clearance (CrCl), mL/min
Source date: DailyMed SPL version 11, posted Nov 17, 2022
Retrieved: 2026-11-07

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 5.2 Renal Impairment/Hyperkalemia/Hypotension when Tekturna HCT is Given in Combination with ARBs or ACEIs / 5.5 Impaired Renal Function / 8.6 Renal Impairment

Use the usual renal dose at CrCl 30-90 mL/min. Safety and efficacy of the fixed combination in severe impairment remain unestablished. Consider the thiazide component and the specific restrictions on concurrent ACE inhibitors or ARBs.

RDM74-tekturna-hct-official-1 · Source locator: Renal guidance: 5.2 Renal Impairment/Hyperkalemia/Hypotension when Tekturna HCT is Given in Combination with ARBs or ACEIs / 5.5 Impaired Renal Function / 8.6 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8df0ca6a-58cf-41fc-b890-5c7fa5a3792c
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min
Source date/version
DailyMed SPL version 11, posted Nov 17, 2022
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
a0bd8a2ae97a7c885afe8b6f5010c39025f9d3e1c24f6e82095a5c33f95ee56c

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-tekturna-hct&s1=RDM74-tekturna-hct-official&h1=35b3c7e3112f858a23b7ecc11b63a8e359b4ae5f41039720fbbe5c338b83bf25

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