One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Historical indication, duration and organism material is retained. This import does not establish that these are preferred current treatment choices.
The 750, 500 and 250 mg renal paths differ. The 250 mg row has a specific uncomplicated-UTI exception and lacks dialysis adjustment information.
What to reconcile: Retain indication, usual dose, loading dose and maintenance interval together.
Open this note and its source referencesDo not select 750, 500 or 250 mg solely from clearance; begin with the indication-specific usual regimen.
Dialysis evidence: A regimen is reported in selected content
Select the indication-specific usual regimen before using the adult renal table.
| Usual regimen | CrCl 20-49 mL/min | CrCl 10-19 mL/min or HD/CAPD |
|---|---|---|
| 750 mg every 24 hours | 750 mg every 48 hours | 750 mg once, then 500 mg every 48 hours |
| 500 mg every 24 hours | 500 mg once, then 250 mg every 24 hours | 500 mg once, then 250 mg every 48 hours |
For the 250 mg/day regimen, no adjustment at 20-49; at 10-19 use 250 mg every 48 hours except uncomplicated UTI, for which the source says no adjustment. No HD/CAPD adjustment information is supplied for that 250 mg row. At CrCl at least 50, the renal table requires no adjustment. Fluoroquinolone boxed warnings and indication restrictions remain separate selection requirements.
RDM61-rxlist-levofloxacin-387b432d8b-C1 · Source locator: Dosage and Administration: renal impairment; named precautions
No new official-label card was obtained for this product in v6.1. Earlier source layers, if present, were retained but not rechecked.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=levofloxacin&s1=RDM61-rxlist-levofloxacin-387b432d8b&h1=3192742a403886a144b8d1cccb751bcfc31b23a81d70ec5c2daefa698178364e