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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
An RX mirror and its underlying label are not independent clinical confirmations.
Check source scope before reading a dose
AUGTYRO: selected RX renal passage
Product / population
AUGTYRO oral capsules for the labeled molecularly selected oncology indication and age group; not a full oncology regimen.
Renal method
eGFR, mL/min as printed in section 8.6
Source revision
Revision date not established in reviewed mirror passage.
Retrieved
2026-11-07
Local review status
Selected sections checked against the identified source; not a complete monograph or independent clinician approval.
Documented differences and cautions on this drug
All record notes are retained here, including notes about sources not selected in this review.
AUGTYRO: source applicability and renal evidence limits
Section 8.6 prints eGFR 30-90; supporting PK wording uses 30 to <90. The dosing summary explicitly follows section 8.6. This is not evidence for a new dialysis recommendation.
What to reconcile: Use the full indication, interactions and toxicity-modification instructions.
GlobalRPh RX List / label mirror · AUGTYRO oral capsules for the labeled molecularly selected oncology indication and age group; not a full oncology regimen.
Renal method: eGFR, mL/min as printed in section 8.6 Source date: Revision date not established in reviewed mirror passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.
Before using this finding
eGFR <30 or dialysis: recommended dose not established.
Dialysis evidence: No dialysis regimen established in selected content
Selected sections checked against the identified source; not a complete monograph or independent clinician approval.
Section 8.6 and supporting 12.3
The selected mirror PK passage reports no meaningful difference with mild/moderate impairment and uncharacterized severe-renal/kidney-failure effects. It does not independently establish a severe-renal dose.
RDM72-repotrectinib-augtyro-rx-1 · Source locator: Section 8.6 and supporting 12.3
Source-specific limits
Selected renal section, not a complete prescribing monograph. A label and its mirror are not independent evidence.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
