One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Opening and detailed source regimens are retained separately where wording differs. Historical infection regimens are not labeled current guideline therapy.
The RX table retains 50% of the indication dose at CrCl <=50 without dialysis. UCSF separates CrCl <10 and uses 25%. Its continuous-dialysis guidance is specifically qualified by CVVHD evidence.
What to reconcile: Select one applicable complete regimen. Do not combine a label percentage with a different institutional dialysis interval.
Open this note and its source referencesDaily IV/oral targets above CrCl 50 mL/min: oropharyngeal disease 100 mg; esophageal disease 200 mg; systemic/severe infection 400 mg at weight <=80 kg, 600 mg at 81-100 kg, or 800 mg above 100 kg. At CrCl 10-50 use half the indication-specific daily target; below 10 use one quarter.
IHD: give 100 mg for oropharyngeal disease, 200 mg for esophageal disease, or 400 mg for severe disease initially and then after HD.
CVVHD: respectively 200 mg daily, 400 mg daily, or 800-1200 mg/day in doses every 12-24 hours. Heme/BMT prophylaxis uses 400 mg daily with normal renal function, 400 mg initially and after IHD, or 800 mg daily during CVVHD.
The higher continuous-treatment doses are CVVHD-specific and were not evaluated for other continuous modalities such as CVVH.
RDM30-016-fluconazole-1 · Source locator: UCSF - fluconazole; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=fluconazole&s1=RDM30-016-fluconazole&h1=2d7b7babf113aa98acdd0a0f2f25860c319d2ba0573fdd13de5f68e7752b6eb6