GlobalRPh Renal Dosing Masterv6.6
Source review / handoff

Rifaximin tablets (adults)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Rifaximin tablets (adults) - selected U.S. labeling

Product / population
Adult oral rifaximin tablets for the labeled traveler-diarrhea, hepatic-encephalopathy-recurrence and IBS-D uses. Not rifampin or rifabutin.
Renal method
No renal pharmacokinetic study or numeric adjustment algorithm in the selected label.
Source revision
Label revision date not separately recorded; retrieval date is not the revision date.
Retrieved
2026-09-05
Local review status
Selected dosing/renal sections read; concise local summary, not full prescribing information.
Official

Rifaximin tablets (adults) - selected U.S. labeling

Open original reference

U.S. product labeling / DailyMed · Adult oral rifaximin tablets for the labeled traveler-diarrhea, hepatic-encephalopathy-recurrence and IBS-D uses. Not rifampin or rifabutin.

Renal method: No renal pharmacokinetic study or numeric adjustment algorithm in the selected label.
Source date: Label revision date not separately recorded; retrieval date is not the revision date.
Retrieved: 2026-09-05

Selected dosing/renal sections read; concise local summary, not full prescribing information.

Labeled basic dosing

IndicationAdult oral schedule
Noninvasive E. coli travelers' diarrhea200 mg three times daily for 3 days
Reduce overt hepatic encephalopathy recurrence550 mg twice daily
IBS with diarrhea550 mg three times daily for 14 days; up to two repeat courses for recurrence

RDM31-rifaximin-label-dose · Source locator: 2.1-2.3

Renal information and dialysis

The label states that renal-impairment pharmacokinetics have not been studied. It does not establish a numeric renal or dialysis regimen. Do not reclassify this as a label-proven no-adjustment statement.

RDM31-rifaximin-label-renal · Source locator: 8.6; 12.3

Selected warnings and limits

Do not use the traveler-diarrhea regimen for fever, bloody stool or suspected invasive pathogens. Severe hepatic disease increases exposure; review P-glycoprotein inhibitors.

RDM31-rifaximin-label-limits · Source locator: 1.1; 5.1, 5.4, 5.5

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c5e8e2fd-7087-4b78-9181-cc259c0be2f1
Retrieved
2026-09-05
DailyMed Set ID
c5e8e2fd-7087-4b78-9181-cc259c0be2f1
Renal-function method
No renal pharmacokinetic study or numeric adjustment algorithm in the selected label.
Source date/version
Label revision date not separately recorded; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or label PDF.
Local summary SHA-256
1fca4a973c5655da1ae8321b4929083bacb61a03b0cda5110b66bf0590a1f1ee

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh v6.6 | RDM66-DIRECT-PHP-20260911 | Local library date 2026-09-11. Selected-card identity does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rifaximin&s1=RDM31-label-rifaximin&h1=21495d2fd8180223521cd388afbd54c0a8bef88d5d1ba450e246b2ddd9c49ac4