One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
Retained GlobalRPh text includes older CrCl-based ceilings. The retrieved RX gout table specifies lower initiation doses without band-specific maxima; the 2020 ACR guideline supports monitored titration to target, including in CKD.
What to reconcile: Do not silently blend old ceilings, new starting doses or cancer-therapy dialysis rows. Reconcile the intended gout regimen, source date and renal measure with a clinician.
Open this note and its source referencesGout initiation and cancer-associated hyperuricemia have different renal tables in the same label. The dialysis schedule belongs to the cancer indication, not a universal gout regimen.
What to reconcile: Select the indication first. An initial low gout dose is not an eGFR-specific maintenance ceiling.
Open this note and its source referencesSelect the indication first. An initial low gout dose is not an eGFR-specific maintenance ceiling.
For impaired-renal gout, increase by 50 mg/day every 2-4 weeks to urate response; an eGFR-specific maximum is not defined.
Renal dosing for recurrent calcium oxalate stones is not established. Pediatric renal instructions are not inferred. Review hypersensitivity, kidney function and interactions.
| eGFR (source prints mL/min) | Source-specific instruction |
|---|---|
| >60 | No renal modification to initial dosing |
| >30 to 60 | 50 mg daily |
| >15 to 30 | 50 mg every other day |
| 5-15 | 50 mg twice weekly |
| <5 | 50 mg weekly |
| eGFR (source prints mL/min) | Source-specific instruction |
|---|---|
| >20 to 60 | No dose modification in this table |
| 10-20 | 200 mg/day |
| <10 | 100 mg/day |
| Setting | Source-specific instruction |
|---|---|
| On dialysis | 50 mg every 12 hours OR 100 mg every 24 hours |
Allopurinol oral - adult GOUT initial dosing
| eGFR (source prints mL/min) | Source-specific instruction |
|---|---|
| >60 | No renal modification to initial dosing |
| >30 to 60 | 50 mg daily |
| >15 to 30 | 50 mg every other day |
| 5-15 | 50 mg twice weekly |
| <5 | 50 mg weekly |
Allopurinol oral - adult CANCER-associated hyperuricemia
| eGFR (source prints mL/min) | Source-specific instruction |
|---|---|
| >20 to 60 | No dose modification in this table |
| 10-20 | 200 mg/day |
| <10 | 100 mg/day |
Allopurinol oral - CANCER indication dialysis
| Setting | Source-specific instruction |
|---|---|
| On dialysis | 50 mg every 12 hours OR 100 mg every 24 hours |
For impaired-renal gout, increase by 50 mg/day every 2-4 weeks to urate response; an eGFR-specific maximum is not defined.
Renal dosing for recurrent calcium oxalate stones is not established. Pediatric renal instructions are not inferred. Review hypersensitivity, kidney function and interactions.
RDM64-official-allopurinol-aa4c5dd87e-C1 · Source locator: Section 2.6 Tables 1 and 2 with footnotes; sections 5 and 7.
For impaired-renal gout, increase by 50 mg/day every 2-4 weeks to urate response; an eGFR-specific maximum is not defined.
Renal dosing for recurrent calcium oxalate stones is not established. Pediatric renal instructions are not inferred. Review hypersensitivity, kidney function and interactions.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=allopurinol&s1=RDM64-official-allopurinol-aa4c5dd87e&h1=1f26bc818e9f96ed884b7aff151d3917c213fd1bcff357024228008f1b172148