GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Duloxetine (Cymbalta)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

Copy is optional; the link can be selected and copied manually. No patient data or dose decision is collected.

Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Cymbalta - labeled renal guidance

Product / population
Duloxetine (Cymbalta), adult delayed-release oral capsules
Renal method
GFR, mL/min as printed in the dosage instruction
Source revision
DailyMed SPL version 3, effective 2016-08-06; posted Aug 08, 2016
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Cymbalta - product and source limitations

Exposure rises in ESRD. The GFR threshold is printed in mL/min in the dosage instruction.

What to reconcile: Verify the current prescribing information for this presentation.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Cymbalta - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Duloxetine (Cymbalta), adult delayed-release oral capsules

Renal method: GFR, mL/min as printed in the dosage instruction
Source date: DailyMed SPL version 3, effective 2016-08-06; posted Aug 08, 2016
Retrieved: 2026-11-07

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2, severe renal impairment and 8.10

Avoid use when GFR is below 30 mL/min. Exposure rises in ESRD. The GFR threshold is printed in mL/min in the dosage instruction.

RDM73-cymbalta-official-1 · Source locator: Renal guidance: 2, severe renal impairment and 8.10

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=00acd9e9-b26a-4626-949e-112ecd2f27e6
Retrieved
2026-11-07
Renal-function method
GFR, mL/min as printed in the dosage instruction
Source date/version
DailyMed SPL version 3, effective 2016-08-06; posted Aug 08, 2016
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
eef8a0bf2e1916719c04b627ce719c07751920835b45da5f31b714560b79b8a5

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=duloxetine&s1=RDM73-cymbalta-official&h1=1d944effbbcf3d4343f34e65ea9b9651556cd38e8b5b8de2efb5f1d7932df1e3

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