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Brukinsa - labeled renal guidance
Product / population
Zanubrutinib (Brukinsa), adult oral products
Renal method
Cockcroft-Gault creatinine clearance, mL/min
Source revision
DailyMed SPL version 25, effective 2026-09-04; posted Sep 14, 2026
At CrCl >=15 mL/min, a renal dose change is unnecessary. Monitor for adverse reactions in patients on dialysis. The effect of dialysis on drug exposure is unknown. Verify the exact dosage form.
RDM73-brukinsa-official-1 · Source locator: Renal guidance: 8.6 and 12.3
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
