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Vytorin - labeled renal guidance
Product / population
Ezetimibe and simvastatin (Vytorin), oral tablet
Renal method
Renal impairment categories as defined by the cited product label
DailyMed / product prescribing information · Ezetimibe and simvastatin (Vytorin), oral tablet
Renal method: Renal impairment categories as defined by the cited product label Source date: DailyMed SPL version 9, posted Jan 23, 2026 Retrieved: 2026-11-07
Renal toxicity or monitoring. On-treatment injury and monitoring instructions are not a baseline renal-dose schedule.
Renal guidance: 2.4 Recommended Dosage in Patients with Renal Impairment / 8.6 Renal Impairment
Mild impairment has no special adjustment. In moderate or severe impairment, doses above ezetimibe 10 mg/simvastatin 20 mg require caution and close monitoring. The dose is written in ezetimibe/simvastatin order. Assess muscle symptoms and interacting drugs.
RDM74-vytorin-official-1 · Source locator: Renal guidance: 2.4 Recommended Dosage in Patients with Renal Impairment / 8.6 Renal Impairment
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.