One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
The label includes CrCl exactly 30 in its >=30 band. UCSF prints >30 and <30, omitting exactly 30, and uses higher doses and different HD scheduling.
What to reconcile: Keep source-specific dose, interval, indication, weight basis and modality together. The official threshold is explicit; seek institutional clarification rather than silently changing its headings.
Open this note and its source referencesIV dosing at CrCl >30 mL/min is 8-10 mg/kg daily; below 30, 8-10 mg/kg every 48 hours. The webpage omits exactly 30. Certain VRE infections may require up to 12 mg/kg with ID pharmacy guidance.
IHD: 8-10 mg/kg initially and after HD; an unstable dialysis schedule may instead use every-48-hour dosing. CVVHD: 6-8 mg/kg daily. Flow above 2.5 L/hour can require higher dosing; obtain specialist input. This continuous regimen has not been evaluated for other modalities such as CVVH.
Weight is total body weight unless it exceeds 120% of ideal body weight, when UCSF uses adjusted weight. Daptomycin is not effective for pneumonia. These high-dose institutional recommendations remain distinct from label regimens.
RDM30-017-daptomycin-1 · Source locator: UCSF - daptomycin: high-dose institutional regimen; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=daptomycin&s1=RDM30-017-daptomycin&h1=122257f13f94c01e2a8f6ecdb4e99af9217f3c42938a385b577afe5c5360f0e9