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Clinical context remains essential
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
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Ayvakit - labeled renal guidance
Product / population
Avapritinib (Ayvakit), adult oral tablets
Renal method
Cockcroft-Gault creatinine clearance, mL/min
Source revision
DailyMed SPL version 16, effective 2026-10-20; posted Oct 26, 2026
At CrCl 30-89 mL/min, no renal reduction is recommended. No dose has been established at CrCl 15-29 or below 15. Confirm the indication-specific starting dose. Neither severe impairment nor ESRD has an established renal regimen here.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
