GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Posaconazole (Noxafil), IV injection only

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Noxafil - labeled renal guidance

Product / population
Posaconazole (Noxafil), IV injection only
Renal method
Indexed GFR/eGFR, mL/min/1.73 m2
Source revision
DailyMed SPL version 56, posted Mar 06, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Noxafil - product and source limitations

Vehicle accumulation is specific to the IV formulation. Do not apply this threshold to oral products.

What to reconcile: Vehicle accumulation is specific to the IV formulation. Do not apply this threshold to oral products.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Noxafil - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Posaconazole (Noxafil), IV injection only

Renal method: Indexed GFR/eGFR, mL/min/1.73 m2
Source date: DailyMed SPL version 56, posted Mar 06, 2026
Retrieved: 2026-11-07

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: Dosage and Administration; renal impairment and injection vehicle precautions

Avoid IV posaconazole when eGFR is below 50 mL/min/1.73 m2 unless the anticipated benefit outweighs the risk of vehicle accumulation. Follow serum creatinine closely. Oral products have different formulation-specific instructions. If creatinine rises, assess switching to an appropriate oral formulation.

RDM74-noxafil-official-1 · Source locator: Renal guidance: Dosage and Administration; renal impairment and injection vehicle precautions

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b073b082-7b57-4423-8c06-4fd4263d6f84
Retrieved
2026-11-07
Renal-function method
Indexed GFR/eGFR, mL/min/1.73 m2
Source date/version
DailyMed SPL version 56, posted Mar 06, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
10ec90d998102aae213f6687c3727076cec5ed4b26138638fb62c094ab18936e

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=rx-noxafil&s1=RDM74-noxafil-official&h1=09a8505c957c95c4df5b09f4c124a366e7c1c28295cd4d31c853de46d7fa917a

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