GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Losartan/hydrochlorothiazide (Hyzaar), adult oral tablets

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

Selecting here opens the current stored cards. The pinned link below records their fingerprints. Do not enter patient information in links or searches.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

Check source scope before reading a dose

Hyzaar - labeled renal guidance

Product / population
Losartan/hydrochlorothiazide (Hyzaar), adult oral tablets
Renal method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 10, effective 2025-11-26; posted Nov 28, 2025
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Hyzaar - product and source limitations

Monitor renal function and potassium. Reassess the combination if renal function declines significantly.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Hyzaar - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Losartan/hydrochlorothiazide (Hyzaar), adult oral tablets

Renal method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date: DailyMed SPL version 10, effective 2025-11-26; posted Nov 28, 2025
Retrieved: 2026-11-07

Limited or unstudied renal evidence. Not studied does not mean no adjustment is required.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 5.4 and 8.8

Safety and effectiveness have not been established in severe renal impairment, defined as CrCl <30 mL/min. Monitor renal function and potassium. Reassess the combination if renal function declines significantly.

RDM73-hyzaar-official-1 · Source locator: Renal guidance: 5.4 and 8.8

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4116ccde-2e23-45f4-b12f-6337df877744
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date/version
DailyMed SPL version 10, effective 2025-11-26; posted Nov 28, 2025
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
0dc74081afe5105105bed94a8ba8fba38d62ab8b989bee3af6dac238dd3f70ee

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=losartan-hctz-hyzaar&s1=RDM73-hyzaar-official&h1=0863c6efa3ef2427f09e5473dcaa9346378db3ab0dd2829b266ceea8db79edb1

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