GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Source review / handoff

Sotatercept-csrk injection (Winrevair)

One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.

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1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.

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Clinical context remains essential

Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.

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Winrevair - labeled renal guidance

Product / population
Sotatercept-csrk (Winrevair), subcutaneous kit
Renal method
GFR/eGFR in mL/min as reported by the source
Source revision
DailyMed SPL version 13, posted Oct 08, 2026
Retrieved
2026-11-07
Local review status
Selected renal passages reviewed; independent clinician adjudication pending.

Documented differences and cautions on this drug

All record notes are retained here, including notes about sources not selected in this review.

Winrevair - product and source limitations

Evidence for severe nondialysis impairment is predictive. Check hemoglobin and platelet monitoring before doses.

What to reconcile: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Open this note and its source references
Official

Winrevair - labeled renal guidance

Open original reference

DailyMed / product prescribing information · Sotatercept-csrk (Winrevair), subcutaneous kit

Renal method: GFR/eGFR in mL/min as reported by the source
Source date: DailyMed SPL version 13, posted Oct 08, 2026
Retrieved: 2026-11-07

Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 12.3 Pharmacokinetics

Measured sotatercept exposure showed no clinically meaningful difference in mild or moderate impairment or in the end-stage kidney disease group receiving dialysis. Evidence for severe nondialysis impairment is predictive. Check hemoglobin and platelet monitoring before doses.

RDM74-winrevair-official-1 · Source locator: Renal guidance: 12.3 Pharmacokinetics

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=21693ee2-cd23-4137-ac67-066bb3a4a9b7
Retrieved
2026-11-07
Renal-function method
GFR/eGFR in mL/min as reported by the source
Source date/version
DailyMed SPL version 13, posted Oct 08, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
9af8db13a47ec2628370891a45d11e98f04dd044de6445b522d744aeb852e4b6

Document the clinical decision separately

This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.

GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.

Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=sotatercept-winrevair&s1=RDM74-winrevair-official&h1=0346f4348d09014cbcc2d00ab2cdcd72fc21b3c669bd61c15d03fa3f97404598

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