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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Streptokinase

Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Streptokinase (opens in a new tab)Original source URL: https://globalrph.com/dilution/streptokinase/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/streptokinase/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:50:48.437362+00:00
Source location
div.post-content
Packaged content SHA-256
a2bcf3c784a8d1127500d68f02ee598a0a26019e6fc56432399eb1e3505464ad
Original response SHA-256
bc2ab7fda3226f37090a14932858dbe29a9269ca06ac0c0ee2325522f8fdd83e
Source body SHA-256
f848b94681096f091d4cd03e0b01c235ad67f0929e8168d383239fcdb9800815

Streptokinase
The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents
NS, D5W

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]
[250,000 u] [50 ml] [30 min]
[1,500,000 u] [50-250ml] [60 min]

Stability / Miscellaneous
Prepare just before use.
Avoid shaking to prevent foaming.

Acute MI: Give 1.5 million IU over 60 minutes.
PE: Loading dose: 250,000 iu over 30 minutes, followed by 100,000 iu/ hr x 24 hours. (x 72 hours for DVT).

Reconstitute the 250, 600, 750k with 5 ml NS. 1.5 mu with 10ml. Do not add more than 1.5 mu to an IV solution (limited stability).

Review contraindications - See Package Insert

Obtain baseline CBC, hct, platelet, PT/PTT, CPK, CPKmb, fibrinogen.
Source: [package insert]

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