Intended users
Healthcare professionals, researchers, and medically sophisticated readers reviewing the evidence landscape.
GlobalRPh evidence-navigation tool
Investigational Peptide Evidence and Safety Navigator (Peptide selection tool)
Select one or more clinical or research topics. The navigator organizes peptide and peptide-drug records by topic-specific evidence and U.S. regulatory status. It does not select a treatment.
Important scope and safety notice
This is not a personalized peptide recommendation tool. It does not identify a "best peptide" and provides no dosing, reconstitution, preparation, administration, cycling, stacking, sourcing, seller comparison, or product-authentication advice. A displayed relationship may reflect an FDA-labeled use, an unapproved use of an approved drug, human investigation, preclinical research, or marketing claims.
Not for emergencies or time-critical decisions. For severe symptoms, suspected poisoning, an acute adverse reaction, or urgent clinical deterioration, use emergency services, Poison Control, or the responsible clinical service rather than this navigator.
Population
General educational review of adult and pediatric evidence where available. Not validated for diagnosis, prescribing, treatment selection, or trial eligibility.
Required input
At least one of 98 clinical or research topics and at least one evidence category. Context flags are optional but strongly encouraged.
Privacy and missing data
Selections are submitted by POST for PHP processing and are not intentionally stored by this application. Server, proxy, security, or hosting logs may still record request metadata. Do not enter patient identifiers.
How evidence categories are separated
FDA approval belongs to a specific finished product, indication, population, and formulation. Approval of a molecule for one use does not convert other uses into approved indications.
FDA-approved for selected topic
A current U.S. FDA-approved finished product has a labeled indication that directly matches the selected topic. Eligibility, formulation, population, and product restrictions still apply.
FDA-approved product; selected use not FDA-approved
The molecule is available in an FDA-approved product, but the selected topic is not a matching FDA-approved use. Human research or off-label clinical use may exist; this category does not imply guideline support or suitability.
Human investigational : unapproved product/program
Human research exists for an unapproved product or selected program, but no matching U.S. FDA-approved product or indication is represented.
Preclinical only
The selected-topic relationship is based primarily on laboratory or animal research. Human benefit and safety are not established.
Primarily anecdotal / marketing-associated
The association is driven mainly by marketing, extrapolation, uncontrolled reports, adverse-effect repurposing, or claims that exceed the evidence.
Navigator results
Select at least one topic, retain at least one evidence category, and submit the form. PHP will generate the complete result on this page.
Methodology, transparency, and update requirements
Decision logic and execution location
PHP validates submitted topic, context, and evidence category identifiers against the curated dataset. Each peptide and topic relationship is assigned one evidence status: FDA approved for the selected topic; FDA approved product but selected use not FDA approved; human investigational for an unapproved product; preclinical only; or primarily anecdotal or marketing associated. PHP orders results by evidence status and then by the number of selected topic matches. This is an evidence navigation order, not a treatment recommendation, comparative effectiveness ranking, or benefit score.
Core execution: Topic validation, context validation, evidence filtering, relation matching, precedence assignment, grouping, ordering, unmatched-topic detection, conventional-alternative assembly, and clinician-summary generation are implemented in PHP. The page remains functional when JavaScript is disabled.
Permitted JavaScript
Embedded JavaScript is limited to interface enhancements: topic search, select-visible and clear controls, display-only result filtering, copy, print, and same-origin iframe-height adjustment. It does not calculate, rank, add, remove, or reinterpret clinical results.
Regulatory interpretation
FDA approval applies to a specific finished product, formulation, population, and indication. Foreign approval, historical approval, compounding, cosmetic availability, or a "research use only" label does not establish current U.S. FDA approval or suitability for human use.
Source interpretation
Direct labels, approval pages, trial records, and PubMed records are identified separately from broad search links. A search link is a discovery aid, not proof of a claim.
Evidence maintenance
Regulatory status, labels, trial phases, safety communications, compounding policy, and anti-doping rules can change. Verify current FDA labeling, Drugs@FDA or DailyMed, ClinicalTrials.gov, primary literature, and applicable professional guidance before publication or clinical use.
Version history
1.3.0, August 4, 2026: Added a self contained JavaScript edition to the release package, synchronized the PHP and JavaScript evidence data, added matching center column iframe files, and expanded release validation.
1.2.0, August 4, 2026: Rewrote the recommended production architecture so core processing occurs in PHP. The production file remains fully functional without JavaScript.
1.1.0, August 4, 2026: Completed the clinical and regulatory prepublication rewrite and dataset correction.
1.0.0, August 4, 2026: Initial development build.
Release status: Version 1.3.0 has undergone dual release packaging, typography, architecture, and regression review. It remains a maintained educational editorial dataset, not a validated medical device or autonomous clinical decision system.