:root{--ink:#163444;--muted:#526a76;--navy:#123c51;--teal:#08748b;--paper:#fff;--line:#cbdde5;--wash:#f0f6f8;--green:#e9f5eb;--amber:#fff4dc}*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:18px}body{margin:0;background:#f0f5f7;color:var(--ink);font-family:Arial,Helvetica,sans-serif;font-size:17px;line-height:1.65}a{color:#066a88;text-underline-offset:3px;overflow-wrap:anywhere}a:hover{color:#003e55}button,input,select{font:inherit}button,a,input,select,summary{touch-action:manipulation}a:focus-visible,button:focus-visible,input:focus-visible,select:focus-visible,summary:focus-visible{outline:3px solid #db8b00;outline-offset:4px}.shell{max-width:1220px;margin:auto;padding:0 24px}.skip{position:absolute;top:-100px;left:14px;padding:12px;background:white;z-index:30}.skip:focus{top:6px}.brandbar{display:flex;justify-content:space-between;align-items:center;gap:16px;padding:19px 0;font-size:15px;border-bottom:1px solid var(--line)}.brandbar>a{text-decoration:none;font-size:22px;font-weight:bold;color:var(--navy)}.brandbar span{font-size:14px;font-weight:normal}.brandbar>a span{margin-left:10px}.breadcrumbs{display:flex;flex-wrap:wrap;gap:10px;font-size:14px;margin:20px 0}.hero{margin:26px 0 22px;padding:38px 40px 34px;border:1px solid #adcad5;border-radius:16px;background:linear-gradient(120deg,#e4f1f7,#f9fcfd 58%,#e8f4ed);box-shadow:0 8px 24px #123c5109}.eyebrow{text-transform:uppercase;letter-spacing:1.3px;font-size:12px;line-height:1.5;font-weight:bold;color:#3c6374;margin-bottom:9px}h1,h2,h3,h4{line-height:1.22;color:var(--navy);overflow-wrap:anywhere}h1{font-size:42px;letter-spacing:-1.2px;margin:10px 0 18px}h1 span{color:#08748b}h2{font-size:27px;margin:8px 0 18px}h3{font-size:23px;margin:4px 0 14px}h4{font-size:19px;margin:24px 0 9px}p{margin:10px 0 17px}.hero p{font-size:19px;max-width:950px}.hero-actions{display:flex;align-items:center;flex-wrap:wrap;gap:12px;margin-top:24px}.button{display:inline-flex;justify-content:center;align-items:center;text-align:center;border:1px solid #08748b;border-radius:7px;background:#08748b;color:white;text-decoration:none;font-weight:bold;padding:10px 17px;cursor:pointer;min-height:46px;line-height:1.4}.button:hover{background:#095e73;color:white}.button.secondary{background:white;color:#075d77;border-color:#9bb8c6}.button.secondary:hover{background:#e8f2f6}.button.small{font-size:14px;padding:8px 12px}.text-link{padding:9px;font-weight:bold}.stat-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:12px;margin:20px 0}.stat-grid>div{padding:15px 18px;background:white;border:1px solid var(--line);border-radius:10px}.stat-grid strong{display:block;color:var(--teal);font-size:30px;line-height:1.3}.stat-grid span{display:block;font-size:14px;line-height:1.45;margin-top:6px}.notice{margin:22px 0;padding:18px 22px;border:1px solid #b2cedb;border-left:5px solid #08748b;border-radius:8px;background:#edf6fa}.notice.caution,.source-warning{background:var(--amber);border-color:#e2c98b;border-left-color:#a7720c}.notice p:last-child{margin-bottom:0}.notice h2{font-size:21px;margin-top:0}.panel,.search-panel{background:white;border:1px solid var(--line);border-radius:12px;padding:25px;margin:25px 0}.section-heading{display:flex;align-items:center;justify-content:space-between;gap:15px;flex-wrap:wrap}.section-heading h2{margin-bottom:12px}.search-form,.search-controls,form{display:flex;align-items:flex-end;gap:12px;flex-wrap:wrap}form label{display:block;flex:1;min-width:180px;font-weight:bold;font-size:14px}form input,form select{display:block;max-width:100%;width:100%;border:1px solid #99b8c7;border-radius:6px;padding:11px 13px;color:var(--ink);background:white;margin:5px 0 0;min-height:48px}form label:first-child{flex:2}form .button{min-height:49px}.az-nav,.az{display:flex;gap:7px;flex-wrap:wrap;margin-top:20px}.az-nav a,.az a{display:flex;align-items:center;justify-content:center;min-width:37px;min-height:40px;padding:5px 11px;background:var(--green);border:1px solid #b3d5bb;border-radius:5px;font-weight:bold;text-decoration:none;color:#245835}.az-nav a[aria-current],.az-nav a.active,.az a.active,.az a[aria-current]{background:#246744;color:white}.result-summary,.results-heading,.results-meta{font-size:15px;margin:20px 0;display:flex;gap:10px;flex-wrap:wrap;align-items:center;justify-content:space-between}.protocol-grid,.cards{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:15px}.protocol-card,.card{background:white;border:1px solid var(--line);border-radius:10px;padding:21px;display:flex;flex-direction:column;min-width:0}.protocol-card h3,.card h3{font-size:23px;margin-bottom:8px}.protocol-card h3 a,.card h3 a{text-decoration:none}.protocol-card p,.card p{font-size:15px;margin:12px 0}.protocol-card .card-bottom,.card-bottom,.card-footer{margin-top:auto;padding-top:14px;display:flex;flex-wrap:wrap;gap:8px;justify-content:space-between;align-items:center;font-size:13px;border-top:1px solid #e3ecef}.tag{font-size:12px;font-weight:bold;padding:4px 9px;border-radius:4px;background:#edf5f8;color:#325565;border:1px solid #d1e2e9;display:inline-block;line-height:1.55}.chips{display:flex;gap:7px;flex-wrap:wrap}.meta,.aliases{font-size:14px;color:var(--muted);overflow-wrap:anywhere}.protocol-hero{padding:27px 28px;border:1px solid var(--line);border-radius:13px;background:linear-gradient(110deg,#e8f3f7,#fff);margin:22px 0}.protocol-hero h1{font-size:36px;letter-spacing:-.6px}.protocol-hero p:last-child{margin-bottom:0}.section-nav{display:flex;flex-wrap:wrap;gap:8px;margin:22px 0}.section-nav a{display:block;font-size:14px;text-decoration:none;border:1px solid #acc9d4;border-radius:6px;padding:9px 12px;background:white;font-weight:bold}.source-group{margin:30px 0}.clinical-section,.evidence-block{padding:23px 26px;background:white;border:1px solid var(--line);border-radius:10px;margin:16px 0;overflow-wrap:anywhere}.clinical-section h3{padding-bottom:13px;border-bottom:2px solid #e4eff3}.clinical-list{padding-left:23px}.clinical-list li{margin:7px 0}.section-foot{display:flex;gap:16px;flex-wrap:wrap;justify-content:space-between;align-items:center;margin-top:20px;padding-top:12px;border-top:1px solid #e3ecef;font-size:13px}.claim{font-size:11px;line-height:1.55;color:#617882;overflow-wrap:anywhere}.source-details{margin-top:20px;padding:14px 17px;background:#f3f7f9;border:1px solid #d9e5eb;border-radius:6px}.source-details summary{font-size:14px;font-weight:bold;cursor:pointer}dl{display:grid;grid-template-columns:170px minmax(0,1fr);gap:10px 16px;font-size:14px;margin:17px 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17px}}@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}}@media print{body{background:white;font-size:11pt}.shell{max-width:none;padding:0}.advert,.skip,.brandbar,.section-nav,.hero-actions,.button,.search-panel,.footer-links,#page-counter{display:none!important}.hero,.protocol-hero,.notice,.panel,.clinical-section,.evidence-block{background:white;box-shadow:none;border:1px solid #aaa;padding:14px;margin:14px 0}.clinical-section h3{break-after:avoid}h1{font-size:24pt}h2{font-size:18pt}h3{font-size:15pt}a{color:inherit}.protocol-grid,.cards,.three-col{display:block}.source-details{display:block}.source-details>summary{display:none}footer{font-size:9pt}.claim{font-size:8pt}}

.search-form{display:block}.search-fields{display:flex;gap:12px;align-items:center;flex-wrap:wrap}.search-fields input{flex:2;min-width:200px}.search-fields select{flex:1.4;min-width:190px}.related .chips{margin-top:10px}@media(max-width:680px){.search-fields>*{flex-basis:100%!important;min-width:0!important}}
/* v3.0: source comparison, counted A-Z, accessible renal tables */
[hidden]{display:none!important}html{scroll-padding-top:16px}.version-badge{font-size:.85rem!important;white-space:normal}.az{gap:7px}.az a{min-width:43px;min-height:55px;display:inline-flex;flex-direction:column;align-items:center;justify-content:center;background:#ecf8ef;font-size:1.12rem;font-weight:700}.az small{font-size:.73rem;font-weight:400}.az a[aria-current=true]{background:#086880;color:#fff}.source-shortcuts{display:flex;flex-wrap:wrap;gap:8px}.source-shortcuts a{white-space:normal;max-width:100%;text-align:left}.protocol-tools{display:flex;gap:14px;align-items:center;flex-wrap:wrap;margin-bottom:12px}.protocol-tools label{display:flex;gap:7px;align-items:center;font-size:.95rem}.protocol-tools input{width:19px;height:19px}.evidence-block{scroll-margin-top:20px;border-left:5px solid #08758b}.source-meta{padding:12px;background:#edf6fa;border-radius:6px;font-size:.92rem}.compare-controls{margin-top:20px;display:flex;gap:10px;flex-wrap:wrap;align-items:center}.comparison-grid{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:18px}.comparison-copy{min-width:0;margin:0!important;padding:18px!important;background:#fff}.comparison-copy h3{font-size:1.2rem}.comparison-copy dl{display:block}.comparison-copy dd{margin:0 0 8px}.table-scroll{max-width:100%;overflow-x:auto;margin:15px 0;border:1px solid #c2d9df;border-radius:7px}.table-scroll table{width:100%;border-collapse:collapse;min-width:380px;font-size:1rem}.table-scroll th,.table-scroll td{padding:11px 12px;text-align:left;vertical-align:top;border-bottom:1px solid #cbdce0}.table-scroll th{background:#e6f3f7}.table-scroll tr:nth-child(even){background:#f6fafc}.source-group{min-width:0}.evidence-block,.clinical-section,.panel{overflow-wrap:anywhere}.source-details{font-size:.88rem}.source-details dd{overflow-wrap:anywhere}.brand-match{font-size:.9rem;background:#f1f8eb;padding:8px;border-radius:5px}.chips>span{font-size:.82rem}.more-results{display:block;margin:22px auto}.record-table{margin-top:20px}.source-review-card{padding:18px;margin-bottom:12px;border:1px solid #bcd3dc;border-radius:9px;background:#fff}.source-review-card .meta{margin:5px 0}.diagnostic dd{font-family:monospace;overflow-wrap:anywhere}#comparison{margin-top:20px}.stat-grid strong{line-height:1.2}.table-scroll:focus,.az a:focus,button:focus-visible,a:focus-visible,input:focus-visible,select:focus-visible{outline:3px solid #d19b24;outline-offset:3px}footer .footer-links{flex-wrap:wrap}.card{min-width:0}.card h3{font-size:1.3rem}.ad-bottom{overflow:hidden;max-width:100%}
@media(max-width:850px){.comparison-grid{grid-template-columns:minmax(0,1fr)}.protocol-tools{gap:10px}.source-picker{padding:16px}.source-shortcuts{display:grid;grid-template-columns:1fr}.hero h1{font-size:2rem}}
@media print{.protocol-tools,.source-picker,.more-results{display:none!important}#comparison:not([hidden]){display:block}.table-scroll{overflow:visible}.table-scroll table{min-width:0}.evidence-block{break-inside:auto}.comparison-grid{display:block}}
/* v3.2: large navigation, name-first search and direct source-section access. */
:root{--nav-height:96px}html{scroll-padding-top:calc(var(--nav-height) + 18px)}body{font-size:18px}.button,.button.small{min-height:52px;font-size:17px;padding:12px 18px}.global-nav{position:sticky;top:0;z-index:40;display:flex;gap:10px;align-items:stretch;flex-wrap:wrap;padding:12px 0;background:#f0f5f7f7;border-bottom:1px solid #b8d2de;backdrop-filter:blur(8px)}.global-nav .button{min-height:62px;flex:1 1 auto;font-size:18px}.global-nav .home-button,.home-button{background:#125637;border-color:#125637;color:#fff;min-height:62px;font-size:20px;font-weight:700}.global-nav .top-button{flex:0 0 74px}.hero{padding:34px 38px}.hero h1{font-size:44px}.hero-actions .button{min-height:58px}.brandbar .version-badge{font-size:14px!important}.breadcrumbs{font-size:15px}.search-panel{border:2px solid #77a6b9;box-shadow:0 5px 20px #153d5108}.quick-search{display:block;margin:18px 0}.quick-search>label,.search-form>label{font-size:18px}.quick-search-row{display:flex;align-items:stretch;gap:10px;margin-top:8px}.suggest-wrap{position:relative;flex:1;min-width:0}.suggest-wrap input{min-height:62px;margin:0;font-size:20px;width:100%;min-width:0}.quick-search-row>.button{min-height:62px}.suggestions{position:absolute;left:0;right:0;top:100%;list-style:none;z-index:60;margin:5px 0 0;padding:5px;border:2px solid #0b6d85;border-radius:8px;background:#fff;box-shadow:0 9px 25px #123c5133;max-height:410px;overflow-y:auto}.suggestions li{margin:0;padding:0}.suggestions [role=option]{display:block;padding:12px;min-height:55px;text-decoration:none;border-bottom:1px solid #dbe5ea;font-size:18px}.suggestions small{display:block;color:#506775;font-size:14px}.suggestions [aria-selected=true],.suggestions [role=option]:hover{background:#e5f3f8;color:#103e50}.filter-grid{display:grid;grid-template-columns:1fr 1fr 1fr;gap:14px;margin-top:17px}.filter-grid label{min-width:0;font-size:15px}.filter-grid select{font-size:16px;min-height:54px}.az{gap:8px}.az a{min-width:56px;min-height:64px;font-size:22px;border:1px solid #a7cbb1;border-radius:7px}.az small{font-size:13px}.results-toolbar{display:flex;gap:15px;justify-content:space-between;align-items:center;flex-wrap:wrap}.result-count{font-size:20px}.card h3{font-size:25px}.card .aliases{font-size:17px}.card-top{display:flex;gap:8px;flex-wrap:wrap;justify-content:space-between}.card p{font-size:17px}.card .review-note{font-size:14px;color:#75510a}.new-tag{background:#eaf5df;color:#315518;border-color:#b2d193}.card-bottom{gap:8px}.card-bottom>.button{flex:1 1 130px}.compact-list{grid-template-columns:1fr}.compact-list .card{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:8px 20px;padding:17px 22px}.compact-list .card-top,.compact-list h3,.compact-list .aliases,.compact-list .review-note,.compact-list .chips{grid-column:1}.compact-list .card-bottom{grid-column:2;grid-row:1 / 6;align-self:center;border:0;padding:0;display:flex;flex-wrap:nowrap}.compact-list .record-summary{display:none}.compact-list .card p{margin:0}.renal-jump-grid{display:grid;grid-template-columns:1fr 1fr;gap:15px}.jump-card{min-width:0;border:1px solid #abc9d6;border-left:5px solid #08748b;border-radius:8px;padding:20px;background:#f7fbfd}.jump-card h3{font-size:22px;margin-top:12px}.jump-card p{font-size:16px}.jump-actions{display:flex;gap:8px;flex-wrap:wrap}.jump-actions .button{flex:1 1 100%;text-align:left;justify-content:flex-start;font-size:17px}.source-return,.footer-actions{display:flex;gap:10px;flex-wrap:wrap;margin-top:24px}.source-return .button{flex:1}.source-shortcuts .button{font-size:17px}.section-nav a{font-size:17px;min-height:54px;display:flex;align-items:center;justify-content:center;text-align:center}.protocol-tools{padding-bottom:9px}.protocol-tools label{min-height:48px;padding:7px}.protocol-tools input{width:23px;height:23px}.source-details summary{font-size:17px;min-height:44px;display:list-item;padding:8px}.clinical-section,.evidence-block{scroll-margin-top:calc(var(--nav-height) + 18px)}h4[id]{scroll-margin-top:calc(var(--nav-height) + 18px)}.shelf-links{display:flex;flex-wrap:wrap;gap:9px}.shelf-links .button{font-size:16px}.personal-shelf h3{margin-top:20px}.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}.jump-flash{outline:3px solid #b87d07;outline-offset:5px}.ad-top{max-width:100%}.advert iframe{max-width:100%}.footer-links>a{padding:10px 0;min-height:44px}.button:disabled{opacity:.55;cursor:not-allowed}.no-suggestions{padding:12px;font-size:16px}
@media(max-width:850px){.renal-jump-grid{grid-template-columns:1fr}.filter-grid{grid-template-columns:1fr}.global-nav .button{font-size:17px}.hero h1{font-size:36px}.compact-list .card{display:flex}.compact-list .card-bottom{align-self:stretch;flex-wrap:wrap}.compact-list .card .record-summary{display:none}}
@media(max-width:600px){:root{--nav-height:200px}.global-nav{display:grid;grid-template-columns:1fr 1fr;gap:7px;padding:8px 0}.global-nav .button{min-height:54px;padding:10px 8px;font-size:16px}.global-nav .home-button{font-size:18px}.global-nav .top-button{display:flex}.shell{padding:0 12px}.hero{padding:24px 20px}.hero h1{font-size:32px}.hero p{font-size:18px}.panel,.search-panel{padding:19px 16px}.quick-search-row{flex-wrap:wrap}.quick-search-row>.suggest-wrap{flex-basis:100%}.quick-search-row>.button{width:100%;min-height:54px}.suggest-wrap input{font-size:18px;min-height:58px}.az{gap:7px}.az a{flex:0 0 calc((100% - 35px)/6);min-width:0;min-height:62px;padding:7px 2px}.az a:first-child{font-size:19px}.card{padding:19px}.card h3{font-size:24px}.renal-finder{padding:18px 14px}.jump-card{padding:16px}.jump-card h3{font-size:21px}.button,.button.small{min-height:52px;font-size:17px}.section-nav a{flex-basis:100%;min-height:52px;font-size:17px}.clinical-section,.evidence-block{padding:18px}.protocol-hero h1{font-size:30px}.source-return .button{flex-basis:100%}.footer-actions .button{width:100%}.brandbar{gap:8px;align-items:flex-start}.brandbar .version-badge{max-width:100px;font-size:12px!important}.stat-grid span{font-size:14px}.table-scroll table{font-size:16px}.suggestions{max-height:310px}.results-toolbar .button{width:100%}}
@media(prefers-reduced-motion:reduce){*,html{scroll-behavior:auto!important;transition:none!important}}
@media print{.global-nav,.quick-search,.renal-finder,.source-return,.footer-actions,.personal-shelf,.results-toolbar,.suggestions{display:none!important}.source-details{display:block!important}.source-details>*{display:block!important}.source-details>summary{display:none!important}html{scroll-padding-top:0}.hero h1{font-size:24pt}.comparison-copy a{overflow-wrap:anywhere}}

/* Keep every dosing column visible on small screens. Labels repeat for each row. */
@media screen and (max-width:680px){
.table-scroll:has(.mobile-stacked){overflow:visible;border:0;border-radius:0}
.table-scroll table.mobile-stacked{display:block;width:100%;min-width:0}
.mobile-stacked thead{position:absolute;width:1px;height:1px;overflow:hidden;clip-path:inset(50%);white-space:nowrap}
.mobile-stacked tbody{display:block;width:100%}
.mobile-stacked tbody tr{display:block;width:100%;border:1px solid #bed3de;border-radius:8px;margin:0 0 16px;overflow:hidden;background:white}
.table-scroll .mobile-stacked tbody td{display:block;width:100%;padding:11px 14px;word-break:normal;overflow-wrap:break-word;font-size:17px;line-height:1.6}
.mobile-stacked tbody td::before{content:attr(data-label);display:block;font-size:14px;line-height:1.4;font-weight:bold;color:#365668;margin-bottom:5px}
.mobile-stacked tbody td:first-child{background:#e8f3f7;font-weight:bold}
.mobile-stacked tbody td:last-child{border-bottom:0}
}

/* v3.3 source audit and differences. Existing large navigation is retained. */
.difference-panel{border:2px solid #b97e16;background:#fffaf0}.difference-card{background:#fff;border:1px solid #e5cf9d;border-radius:10px;padding:22px;margin:18px 0}.difference-card h3{margin-top:12px}.difference-card .jump-actions{display:flex;flex-wrap:wrap;gap:10px}.difference-card .button{max-width:100%;white-space:normal}.difference-badge{display:block;padding:5px 10px;border:1px solid #d7b877;border-radius:5px;background:#fff4dc;font-weight:bold}.audit-promo{background:linear-gradient(110deg,#e9f6f4,#fff);border-left:6px solid #08748b}.audit-tabs{display:flex;gap:12px;flex-wrap:wrap;margin:24px 0}.audit-form{display:flex;align-items:end;gap:12px;flex-wrap:wrap}.audit-record{padding:20px;border:1px solid var(--line);border-radius:10px;margin:16px 0;background:white}.audit-record .chips{margin:16px 0}.audit-record .chips a{min-height:48px;white-space:normal;max-width:100%}.audit-record h3{font-size:21px}.audit-status{display:inline-block;border:1px solid #b6cdd7;border-radius:5px;padding:6px 10px;background:#eef5f8;font-size:14px;font-weight:bold}.audit-dir-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px}.audit-dir-grid article{border:1px solid var(--line);padding:18px;border-radius:9px;min-width:0}.audit-dir-grid h3{font-size:30px}.audit-dir-grid .button{width:100%}.audit-queue details{padding:15px;border-bottom:1px solid var(--line)}.audit-queue summary{cursor:pointer;min-height:48px;font-weight:bold}.evidence-block:target,.difference-card:target{outline:3px solid #d09a2d;outline-offset:3px}.audit-summary{font-size:18px}
@media(max-width:680px){.audit-dir-grid{grid-template-columns:1fr 1fr}.difference-card{padding:18px}.difference-card .jump-actions .button,.audit-tabs .button{width:100%}.audit-dir-grid article{padding:12px}.audit-dir-grid .button{font-size:15px;padding:12px 8px}.audit-form{display:block}.audit-form>*{margin:10px 0}}
@media print{.audit-tabs,.audit-form,.audit-promo{display:none}.difference-panel,.difference-card{background:white;border-color:#999}}

/* v3.4 clinician tools */
.clinician-tools{border-top:6px solid #08749a}.quick-compare-actions{display:flex;flex-wrap:wrap;gap:12px;margin:14px 0 22px}.quick-compare-form{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:16px;align-items:end}.quick-compare-form label,.context-grid label{font-weight:700;display:block;min-width:0}.quick-compare-form select,.context-grid select{display:block;width:100%;max-width:100%;min-height:54px;margin-top:7px;font-size:1rem;background:white;border:1px solid #708a98;border-radius:8px;padding:10px}.quick-compare-form>.button{grid-column:1/-1;width:max-content;max-width:100%}.context-checklist{margin-top:22px;border:1px solid #9bb9c8;border-radius:10px;padding:14px;background:#f4f9fc}.context-checklist>summary{font-size:1.13rem;font-weight:700;cursor:pointer;min-height:44px;line-height:1.5}.context-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px;margin:18px 0}.context-checklist .notice p{margin:.7em 0}.guide-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:20px}.guide-card{border:1px solid #b4c8d0;border-radius:10px;padding:20px;background:white}.guide-card h3{margin-top:0}.guide-step{color:#075a79;font-size:.9rem;font-weight:bold;text-transform:uppercase}.attempt-tools{display:flex;flex-wrap:wrap;gap:12px;align-items:end}.attempt-card{border-bottom:1px solid #bdd0d8;padding:18px 0}.attempt-card:last-child{border-bottom:0}.attempt-card .button{margin:5px 6px 5px 0}.clinical-tools select:focus,.context-grid select:focus{outline:3px solid #146f91;outline-offset:2px}#comparison{scroll-margin-top:110px;margin:22px 0;border-top:3px solid #08749a;padding-top:14px}.comparison-grid>*{min-width:0;overflow-wrap:anywhere}.guide-note{border-left:5px solid #ad7400;padding:14px 18px;background:#fff5d9}
@media(max-width:760px){.quick-compare-form,.context-grid,.guide-grid{grid-template-columns:minmax(0,1fr)}.quick-compare-form>.button{width:100%}.quick-compare-actions .button{flex:1 1 100%}.clinician-tools{padding:18px 14px}.context-checklist{padding:12px}.guide-card{padding:16px}.quick-compare-form select{font-size:16px}#comparison{scroll-margin-top:155px}}
@media print{.quick-compare-form,.quick-compare-actions,.context-checklist,.attempt-tools{display:none}#comparison .comparison-grid{display:block}}

/* v3.5 source-type and review-outline controls */
.progress-callout{padding:18px;border-left:5px solid #117d66;background:#eef8f4;border-radius:8px;line-height:1.7}
.finding-notice{margin:16px 0;line-height:1.6}
.review-outline{border:1px solid #9db8c6;border-radius:10px;padding:16px;margin-top:18px;background:#f6fafd}
.review-outline summary{font-size:1.12rem;font-weight:700;min-height:46px;cursor:pointer}
.review-outline label{display:block;font-weight:700;margin:16px 0 8px}
.review-outline textarea{box-sizing:border-box;width:100%;min-height:250px;resize:vertical;white-space:pre-wrap;overflow-wrap:anywhere;font:1rem/1.5 Arial,Helvetica,sans-serif;padding:14px;border:1px solid #6b8c9e;border-radius:6px}
.review-outline .button{min-height:54px;margin-top:10px}.review-outline .button:disabled{opacity:.55;cursor:not-allowed}
.audit-progress{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px;margin:20px 0}.audit-progress>div{padding:18px;border:1px solid #a8c7d1;border-radius:10px;background:#eff8fa}.audit-progress strong{font-size:1.8rem;display:block}.audit-progress span{display:block;line-height:1.5}
.audit-attempt-list details{margin:10px 0;border:1px solid #c4d5dd;border-radius:8px;padding:14px;overflow-wrap:anywhere}.audit-attempt-list summary{min-height:44px;cursor:pointer;font-weight:700}
.audit-source-links{display:flex;flex-wrap:wrap;gap:10px}.audit-source-links .button{white-space:normal;text-align:left;overflow-wrap:anywhere}
@media(max-width:680px){.audit-progress{grid-template-columns:1fr}.review-outline{padding:12px}.audit-form{grid-template-columns:1fr}.audit-dir-grid{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media print{.review-outline{break-inside:avoid}.review-outline button{display:none}}

/* v3.7 clinical-text finder: large controls, bounded reflow, no hidden source text. */
.drug-text-finder{border-top:5px solid #16755d}
.drug-find-input-row{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:12px;align-items:stretch;margin:8px 0 12px}
#drug-find-input{width:100%;min-width:0;min-height:56px;font:inherit;padding:12px;border:2px solid #759994;border-radius:8px;box-sizing:border-box}
.drug-find-controls,.drug-find-shortcuts{display:flex;gap:10px;flex-wrap:wrap;align-items:center;margin:12px 0}
.drug-find-controls .button,.drug-find-shortcuts .button,.drug-find-input-row .button{min-height:54px;font-size:1rem}
.drug-find-shortcuts .button{padding:12px 18px}
#drug-find-status{overflow-wrap:anywhere}
.rdm-text-match{background:#fff0a6;color:#142b36;border-radius:2px;scroll-margin-top:145px}
.rdm-text-match.current-match{background:#ffc75b;color:#102532;outline:3px solid #925514;outline-offset:2px}
.drug-find-floating{position:sticky;z-index:25;display:grid;grid-template-columns:minmax(0,1fr) auto;gap:10px;align-items:center;background:#f0f8f5;border:2px solid #54897b;border-radius:10px;padding:10px;box-shadow:0 3px 12px #1234;margin-bottom:15px}
.drug-find-floating[hidden]{display:none}.drug-find-floating .button{min-height:48px;padding:10px 16px}.drug-find-floating .match-caption{min-width:0}.drug-find-floating span{display:block;font-weight:700}.drug-find-floating #drug-find-source{font-size:.86rem;font-weight:500;line-height:1.3;overflow-wrap:anywhere;margin-top:3px}.match-actions{display:flex;gap:8px}.match-actions .button{flex:1 1 auto}
@media(max-width:640px){.drug-find-floating{grid-template-columns:1fr}.match-actions .button{padding:10px 12px}}
.v37-alert{border-left:7px solid #ae542c;font-size:1.05rem}
.source-clinical-text{min-width:0;overflow-wrap:anywhere}
@media(max-width:640px){.drug-find-input-row{grid-template-columns:1fr}.drug-find-controls .button{flex:1 1 130px}.drug-find-shortcuts .button{flex:1 1 90px}}
@media print{.drug-text-finder,.drug-find-floating{display:none}.rdm-text-match,.rdm-text-match.current-match{background:transparent;color:inherit;outline:0}}

/* v3.7: source scope never hides clinical text or warnings. */
#drug-find-scope{display:block;width:100%;max-width:100%;min-width:0;min-height:54px;font:inherit;padding:10px 12px;border:2px solid #578396;border-radius:8px;background:#fff;color:#183847;text-overflow:ellipsis}
.drug-text-finder form,.drug-text-finder label{min-width:0;max-width:100%}
.v37-alert{border-left:7px solid #a95011}
@media print{#drug-find-scope-help{display:none}}
/* v3.8: cross-drug source-difference directory; no source ranking or hidden cautions. */
.v38-alert{border-left:7px solid #a95011;font-size:1.05rem}
.difference-form{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:16px}
.difference-form label{min-width:0!important;display:block}.difference-form input[type=search],.difference-form select{width:100%;min-height:56px;font-size:18px}
.difference-form .hero-actions{grid-column:1/-1}.difference-form .difference-checkbox{display:flex;gap:12px;align-items:center;min-height:52px;grid-column:1/-1}.difference-checkbox input{width:24px;height:24px;flex:0 0 24px}
.difference-directory-grid{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:20px}
.difference-directory-card{background:#fff;border:1px solid #b2cbd5;border-top:5px solid #14718a;border-radius:10px;padding:24px;min-width:0;overflow-wrap:anywhere;scroll-margin-top:calc(var(--nav-height) + 22px)}
.difference-directory-card h2{font-size:25px;margin:16px 0 10px}.difference-directory-card h3{font-size:21px}.difference-directory-card p{font-size:17px}.difference-directory-card .notice{padding:14px 17px}.difference-directory-card .notice p{margin-bottom:0}
.difference-source-identities{border-top:1px solid #c9dbe2;border-bottom:1px solid #c9dbe2;padding:10px 0}.difference-source-identities summary{padding:10px 4px;min-height:48px;font-weight:700;cursor:pointer}.difference-source-identity{padding:12px 0}.difference-source-identity+.difference-source-identity{border-top:1px solid #c9dbe2}.difference-source-identity .button{width:100%;text-align:left}.difference-source-identity .meta{font-size:15px}
.difference-pagination{display:flex;flex-wrap:wrap;gap:15px;align-items:center;justify-content:center;padding:26px 0}.difference-pagination .button{min-height:56px}.difference-directory-card .jump-actions{margin-top:15px}.difference-directory-card .jump-actions .button{min-height:56px}
@media(max-width:820px){.difference-directory-grid,.difference-form{grid-template-columns:minmax(0,1fr)}.difference-directory-card{padding:20px}.difference-form .hero-actions .button{width:100%}}
@media print{.difference-form,.difference-pagination{display:none}.difference-directory-grid{display:block}.difference-directory-card{break-inside:avoid;border:1px solid #999;box-shadow:none;margin:16px 0}}
/* v3.9 source-review handoff: large controls, intact scope, printable cautions. */
.handoff-intro{margin:18px 0}.handoff-intro p{margin:8px 0 14px}.handoff-source-action{margin:12px 0}
.handoff-grid,.handoff-form-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:20px}
.handoff-form-grid{margin-bottom:16px}.handoff-form-grid label{display:flex;flex-direction:column;font-weight:700;gap:8px}
.handoff-form-grid select{width:100%;max-width:100%;min-height:54px;font-size:1rem;padding:12px}
.handoff-grid>article{min-width:0;overflow-wrap:anywhere}.handoff-grid dl{margin:0}.handoff-grid dt{font-weight:700;margin-top:12px}.handoff-grid dd{margin:5px 0 16px}
.handoff-scope article{border:1px solid #b3c8d1;background:#f3f8fa;border-radius:10px;padding:18px}
.handoff-share textarea{display:block;box-sizing:border-box;width:100%;min-height:112px;resize:vertical;font-family:ui-monospace,monospace;font-size:14px;line-height:1.55;padding:14px;margin:10px 0 16px;border:1px solid #9fb6c4;border-radius:8px;overflow-wrap:anywhere}
.handoff-share .hero-actions{flex-wrap:wrap}.handoff-page .protocol-hero h1{overflow-wrap:anywhere}.handoff-source-grid .protocol-tools{display:none}.handoff-source-grid .source-details{font-size:.92rem}.handoff-source-grid .source-details dd{overflow-wrap:anywhere}
.handoff-caution{padding:12px 0;border-top:1px solid #c9d7de}.handoff-print-url{overflow-wrap:anywhere;font-size:12px}.handoff-page .handoff-source-grid .source-return{flex-wrap:wrap}
@media(max-width:900px){.handoff-grid,.handoff-form-grid{grid-template-columns:1fr}.handoff-page .hero-actions .button{flex:1 1 230px}.handoff-source-grid .evidence-block{padding:16px}}
@media print{.handoff-select,.handoff-share,.handoff-page .hero-actions,.handoff-source-grid .source-return{display:none!important}.handoff-grid{display:block}.handoff-page .panel,.handoff-page .notice{box-shadow:none!important;border:1px solid #777}.handoff-source-grid article{break-inside:auto}.handoff-caution,.handoff-scope article{break-inside:avoid}.handoff-warning,.handoff-cautions,.handoff-print-context,.handoff-print-url{display:block!important}.handoff-source-grid .source-details{display:block!important}.handoff-print-url{font-size:8pt}.handoff-page h3,.handoff-page h4{break-after:avoid}}

/* v4.3 clinical-focus finder: topic labels are not dosing recommendations. */
.focus-form{display:grid;grid-template-columns:1fr 1fr;gap:18px}.focus-form label{display:block;font-weight:700}.focus-form input[type=search],.focus-form select{width:100%;min-height:54px;margin-top:7px;font:inherit;padding:12px;border:1px solid #91a9b5;border-radius:8px;background:#fff;color:#183342}.focus-options,.focus-form .hero-actions{grid-column:1/-1}.focus-options{display:flex;flex-wrap:wrap;gap:14px 24px}.focus-options label{display:flex;align-items:center;gap:10px;min-height:48px}.focus-options input{width:22px;height:22px;flex:0 0 auto}.focus-results-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px}.focus-card{min-width:0;background:#fff;border:1px solid #bad0d7;border-radius:12px;padding:22px;overflow-wrap:anywhere}.focus-card h2{font-size:1.35rem;line-height:1.3;margin:14px 0 10px}.focus-card h3{font-size:1.08rem;line-height:1.45}.focus-card .card-top{flex-wrap:wrap;justify-content:flex-start;gap:6px}.focus-card .tag{white-space:normal}.focus-card details>summary{cursor:pointer;min-height:48px;display:flex;align-items:center;font-weight:700}.focus-card .jump-actions{display:flex;flex-direction:column;gap:10px}.focus-card .jump-actions .button{min-height:54px;white-space:normal;text-align:center}.focus-card .focus-caution{font-size:.96rem}.focus-caution-count{border-top:1px solid #d6e2e8;padding-top:14px}.focus-card a:focus-visible,.focus-form input:focus-visible,.focus-form select:focus-visible{outline:3px solid #006d96;outline-offset:3px}@media(max-width:800px){.focus-form,.focus-results-grid{grid-template-columns:1fr}.focus-options{display:block}.focus-card{padding:18px}.focus-options label{margin:6px 0}.focus-form .hero-actions .button{width:100%}}@media print{.focus-form,.focus-launch{display:none}.focus-results-grid{display:block}.focus-card{break-inside:avoid;border:1px solid #777;margin-bottom:16px}.focus-card details{display:block}}
#focus-results,.focus-card{scroll-margin-top:calc(var(--nav-height) + 18px)}.focus-card .review-note{font-size:.92rem;padding:10px 12px;border-left:3px solid #a66a00;background:#fff6e4;color:#674807}

/* v4.3: provenance-family filters remain visually neutral, never a quality score. */
.focus-form select{min-height:54px;width:100%;max-width:100%;font-size:1rem}.family-tag{border:1px solid #799ba8;background:#eaf2f5;color:#193d4b}.focus-card .card-top{flex-wrap:wrap;gap:.4rem}.focus-form>label{min-width:0}.focus-options{grid-column:1/-1}
@media(max-width:650px){.focus-form{grid-template-columns:1fr}.focus-form .hero-actions{display:grid;grid-template-columns:1fr}.focus-form .button{min-height:54px;justify-content:center;text-align:center}}

/* v4.3 manual renal-measure filter: wrap long labels without page overflow. */
.focus-form label{min-width:0}.focus-form select{max-width:100%;width:100%;min-width:0}
.metric-classification{padding:10px 12px;border-left:4px solid #177a75;background:#eef8f5;overflow-wrap:anywhere}
#metric-coverage p{max-width:84ch}#focus-metric{font-size:1rem}

/* v4.3 coverage-aware lookup: classification is not source quality or eligibility. */
.coverage-choice{font-weight:700;line-height:1.5}.coverage-breakdown{margin:20px 0}.coverage-breakdown h2{font-size:23px}.coverage-status{padding:12px 14px;border:1px solid #9bb9c6;border-left:5px solid #35667c;border-radius:6px;font-weight:700;font-size:16px;line-height:1.5}.coverage-status.needs-review{background:#fff7e9;border-color:#b69148;color:#624714}.coverage-status.label-match{background:#eef6fa;color:#213e50}.coverage-choice input{flex:none;min-width:24px;min-height:24px}.coverage-breakdown .button{min-height:54px} @media(max-width:600px){.coverage-breakdown h2{font-size:21px}.coverage-choice{display:flex!important;align-items:flex-start;gap:10px}.coverage-choice input{margin-top:4px}.coverage-status{overflow-wrap:anywhere}}

/* v4.4: product-safe navigation and evidence-stage explorer */
.formulation-gate{border:2px solid #507982;background:#f1f8f7}.formulation-gate .jump-actions{display:flex;flex-wrap:wrap;gap:12px;margin:12px 0 20px}.formulation-gate [aria-current="page"]{outline:3px solid #345961;outline-offset:2px;font-weight:700}.review-point-links{display:flex;flex-wrap:wrap;gap:12px;margin:14px 0}.verification-stage-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:12px;margin:16px 0}.verification-stage-grid>div{padding:16px;border:1px solid #b8cace;border-radius:8px;background:#f8fbfc}.verification-stage-grid strong,.verification-stage-grid span{display:block}.verification-stage-grid strong{font-size:1.35rem}.verification-record{border:1px solid #b8cace;border-radius:10px;padding:20px;margin:16px 0;overflow-wrap:anywhere}.verification-record h3{font-size:1.2rem}.verification-record .verification-stage-grid{grid-template-columns:repeat(3,minmax(0,1fr))}.verification-record .verification-stage-grid strong{font-size:1rem}.verification-pagination{display:flex;flex-wrap:wrap;align-items:center;gap:14px;margin:20px 0}.verification-hold{border-left:6px solid #ab7026}.verification-meta{font-size:.95rem;overflow-wrap:anywhere}.verification-form{display:grid;grid-template-columns:2fr 1fr 2fr;gap:14px;align-items:end}.verification-form label{display:flex;flex-direction:column;gap:6px}.verification-form input,.verification-form select{width:100%;min-height:48px;font:inherit}.verification-form-actions{display:flex;flex-wrap:wrap;gap:12px;grid-column:1/-1}
@media(max-width:720px){.verification-stage-grid,.verification-record .verification-stage-grid{grid-template-columns:1fr 1fr}.verification-form{grid-template-columns:1fr}.formulation-gate .button,.review-point-links .button{width:100%;text-align:left}.verification-record{padding:16px}.verification-stage-grid>div{padding:12px}}
@media print{.verification-form,.verification-pagination{display:none}.verification-record{break-inside:avoid}.verification-stage-grid{display:block}.verification-stage-grid>div{display:inline-block;vertical-align:top;min-width:20%}}

/* v4.4 mobile review: avoid narrow, word-fragmented action buttons. */
.verification-form-actions .button{flex:1 1 220px;overflow-wrap:normal;word-break:normal;min-height:54px}
@media(max-width:720px){.verification-form-actions{display:grid;grid-template-columns:1fr;width:100%}.verification-form-actions .button{width:100%;text-align:center;justify-content:center}}

/* v4.7: full-label touch target without an oversized checkbox. */
.verification-form label.review-new-toggle{flex-direction:row;align-items:center;gap:12px;min-height:54px;padding:12px;border:1px solid var(--line);border-radius:6px}.verification-form .review-new-toggle input[type=checkbox]{width:22px;height:22px;min-height:22px;flex:0 0 22px;margin:0}

/* v5.0: full-label touch targets for both coverage opt-ins. */
.focus-options .coverage-choice{min-height:54px}
/* v5.9 source-first navigation and isolated medication workspace */
.evidence-navigator{border:2px solid #8ab8c1;border-left:7px solid #08768a;background:#f3fafb}.evidence-nav-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px}.evidence-nav-card{padding:20px;border:1px solid #afccd3;border-radius:10px;background:#fff;min-width:0}.evidence-nav-card h3{font-size:1.25rem;line-height:1.4;margin:12px 0}.evidence-nav-card .finding-notice{font-size:.94rem;padding:12px}.evidence-nav-card .evidence-scope{font-size:1rem}.evidence-nav-actions{display:flex;gap:10px;flex-wrap:wrap;align-items:stretch}.evidence-nav-actions .button{min-height:48px;max-width:100%}.source-original a,.source-reference-visible a{color:inherit;text-decoration:none;display:block}.source-reference-visible .button{padding:0}.source-reference-visible a{padding:12px 18px}.evidence-nav-card .source-original{padding:0}.evidence-nav-card .source-original a{padding:12px 16px}.caution-link{background:#f7ead0;color:#173342;border-color:#b8a16a}.medication-frame{border:1px solid #adc8d0;width:100%;min-height:1050px;border-radius:10px;background:#fff;display:block}.med-workspace-wrap{padding:0;overflow:hidden}.evidence-nav-card:target,.evidence-block:target{outline:3px solid #08768a;outline-offset:4px}.global-nav{flex-wrap:wrap}.protocol-hero .chips{align-items:center}.protocol-hero .chips .button{font-size:1rem}.evidence-nav-card p{overflow-wrap:anywhere}
@media(max-width:720px){.evidence-nav-grid{grid-template-columns:1fr}.evidence-nav-card{padding:15px}.evidence-nav-actions{flex-direction:column}.evidence-nav-actions .button{width:100%}.evidence-navigator{padding:18px}.medication-frame{min-height:1150px}}
@media print{.evidence-navigator{break-inside:auto}.medication-frame{display:block}.source-original{display:none}}

.evidence-nav-card:only-child{grid-column:1 / -1}

/* v5.9: high-visibility, source-linked qualifications without hiding evidence */
.review-first{background:#fff5dc;border:1px solid #dfc586;border-left:7px solid #a36c12;padding:24px;border-radius:12px;margin:20px 0}.review-first h2{font-size:1.5rem;line-height:1.3;margin:10px 0}.review-first .jump-actions{display:flex;flex-wrap:wrap;gap:10px}.review-first a{min-height:46px;white-space:normal;overflow-wrap:anywhere}.review-first .meta{margin-bottom:0}@media(max-width:600px){.review-first{padding:18px}.review-first .jump-actions a{width:100%}}@media print{.review-first{break-inside:avoid;border:2px solid #333;background:white}}

/* v5.9: dated source updates; preserve the full source history. */
.latest-source-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px;margin:18px 0}.latest-source-grid article{min-width:0;border:1px solid #bdd7d7;border-radius:12px;padding:18px;background:#f3faf8}.latest-source-grid h3{margin:.6em 0;font-size:1.15rem}.latest-source-grid p{overflow-wrap:anywhere}.rx-entry-observation{margin:12px 0;padding:12px;border:1px solid #d4dee5;border-radius:8px}.rx-entry-observation summary{min-height:44px;cursor:pointer;font-weight:700}.latest-source-updates>.button{margin-top:12px}@media(max-width:700px){.latest-source-grid{grid-template-columns:1fr}}

/* v5.9: source-linked dialysis distinctions and dated-label limits. */
.dialysis-evidence-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(min(100%,280px),1fr));gap:16px}.dialysis-evidence-grid article{padding:18px;border:1px solid #a9c5ce;border-radius:10px;background:#f4f9fa;min-width:0}.dialysis-evidence-label{padding:12px;border-left:4px solid #326b7b;background:#eef6f8;overflow-wrap:anywhere}.source-currency-hold{border-left:5px solid #965e0b;background:#fff5de;overflow-wrap:anywhere}.source-currency-hold p{margin-bottom:0}.dialysis-evidence-panel .button{min-height:44px;white-space:normal} @media(max-width:620px){.dialysis-evidence-grid{grid-template-columns:1fr}}

/* Source-specific clinical review prompts; no patient dosing inference. */
.renal-decision-checkpoints{margin:14px 0;padding:16px 18px;border:1px solid #a7c6bc;border-left:5px solid #267164;border-radius:8px;background:#eff8f4;overflow-wrap:anywhere}.renal-decision-checkpoints p{margin:10px 0 0}.renal-decision-checkpoints strong{display:block;font-size:1.04rem}